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老年综合征的发生频率和发生率按年龄组划分:2013 年至 2017 年土耳其单中心经验。

Frequency and coincidence of geriatric syndromes according to age groups: single-center experience in Turkey between 2013 and 2017.

机构信息

Department of Geriatric Medicine, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey,

Department of Geriatric Medicine, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.

出版信息

Clin Interv Aging. 2018 Oct 4;13:1899-1905. doi: 10.2147/CIA.S180281. eCollection 2018.

Abstract

BACKGROUND

Geriatric syndromes are complex clinical manifestations that are not an isolated disease in older adults and have common risk factors within themselves. The syndromes are significant causes of mortality, morbidity, and increased health care costs.

OBJECTIVE

To determine the frequency of geriatric syndromes such as malnutrition, dementia, depression, falls, polypharmacy, urinary incontinence, pressure ulcer, sarcopenia, and frailty in community-dwelling older adults.

METHODS

A total of 2,816 patients, who applied to geriatric outpatient clinic and were evaluated by comprehensive geriatric assessment, were included in this cross-sectional retrospective study. Falls in the last year and urinary incontinence were recorded. Polypharmacy was accepted as concurrent use of more than four drugs. Diagnosis of dementia and depression was defined according to Diagnostic and Statistical Manual of Mental Disorders Fifth Edition diagnostic criteria. In addition, frailty and sarcopenia were evaluated according to Fried's physical frailty scale and European Working Group on Sarcopenia criteria, respectively.

RESULTS

The frequency of polypharmacy was 54.5%, urinary incontinence 47.6%, malnutrition 9.6%, depression 35.1%, dementia 21.6%, falls 33.6%, sarcopenia 31.7%, and frailty 28.3%. When all the participants were divided into three groups (60-69, 70-79, ≥80 years), all syndromes were significantly increased with age, except for depression. While 20% of cases in 60-69 years age group did not have any syndromes, 48% of cases in ≥80 years had more than four syndromes simultaneously.

CONCLUSION

The frequency and coincidence of geriatric syndromes, except for depression, increases with age. Therefore, clinicians other than geriatricians taking care of older people should be aware of these syndromes as well as their treatment mechanisms.

摘要

背景

老年综合征是一种复杂的临床表现,不是老年人中孤立的疾病,本身有共同的危险因素。这些综合征是导致死亡率、发病率和增加医疗保健费用的重要原因。

目的

确定营养不良、痴呆、抑郁、跌倒、多重用药、尿失禁、压疮、肌少症和衰弱等老年综合征在社区居住的老年人中的发生频率。

方法

本横断面回顾性研究共纳入 2816 名接受综合老年评估的老年门诊患者。记录了过去一年的跌倒和尿失禁情况。多重用药被定义为同时使用超过四种药物。根据《精神障碍诊断与统计手册第五版》的诊断标准,诊断痴呆和抑郁。此外,根据 Fried 身体虚弱量表和欧洲肌肉减少症工作组标准,分别评估虚弱和肌少症。

结果

多重用药的发生率为 54.5%,尿失禁 47.6%,营养不良 9.6%,抑郁 35.1%,痴呆 21.6%,跌倒 33.6%,肌少症 31.7%,衰弱 28.3%。当所有参与者被分为三组(60-69 岁、70-79 岁、≥80 岁)时,除了抑郁,所有综合征都随着年龄的增长而显著增加。在 60-69 岁年龄组中,20%的病例没有任何综合征,而在≥80 岁年龄组中,48%的病例同时有超过四种综合征。

结论

除了抑郁,老年综合征的发生频率和同时发生的频率随着年龄的增长而增加。因此,照顾老年人的医生以外的临床医生也应该了解这些综合征及其治疗机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b3d/6174888/2e90f56e2621/cia-13-1899Fig1.jpg

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