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超级肥胖患者(BMI≥60kg/m²)行 Roux-en-Y 胃旁路术与袖状胃切除术的疗效比较:单所大学的 6 年随访结果。

Outcomes of Roux-en-Y gastric bypass versus sleeve gastrectomy in super-super-obese patients (BMI ≥60 kg/m): 6-year follow-up at a single university.

机构信息

Department of General and Digestive Surgery, University Hospital Bichat Claude Bernard Paris France, Paris, France.

Department of General and Digestive Surgery, University Hospital Bichat Claude Bernard Paris France, Paris, France.

出版信息

Surg Obes Relat Dis. 2019 Jan;15(1):23-33. doi: 10.1016/j.soard.2018.09.487. Epub 2018 Oct 11.

Abstract

BACKGROUND

Among the population of morbidly obese people, super-super-obese (SSO) individuals (body mass index >60 kg/m) present a treatment challenge for bariatric surgeons.

OBJECTIVES

To compare the long-term outcomes between laparoscopic sleeve gastrectomy (SG) and laparoscopic Roux-en-Y gastric bypass (RYGB) and to evaluate the efficacy of SG as a stand-alone bariatric procedure for SSO patients.

SETTING

University hospital, Paris, France.

METHODS

We retrospectively reviewed the data outcomes of 210 SSO patients who underwent SG or RYGB between January 2000 and December 2011. The 6-year follow-up data were analyzed and compared.

RESULTS

Follow-up data at 6 years were collected for 57.1% and 52.1% of patients in the SG group and RYGB groups, respectively. Both procedures were effective at promoting weight loss. Most weight loss was achieved at 24 months with both procedures. The average percent excess weight loss and change in body mass index of SG versus RYGB showed no significant differences at the 4-year follow-up. Except for sleep apnea, RYGB showed slightly better resolution of the evaluated co-morbidities. The composite endpoint of major short-term adverse events (<30 d) occurred in 11.7% of patients with RYGB and 6.4% of those with SG (P = .02). Postoperative complications were seen in 26% of RYGB patients and 16.1% of SG patients.

CONCLUSIONS

SG as a primary procedure for SSO patients remains effective even though RYGB achieves better midterm outcomes. SG can be proposed as the primary-option p+rocedure. Further investigations are needed to identify the ideal procedure for patients with symptoms of gastroesophageal reflux disease.

摘要

背景

在病态肥胖人群中,超级肥胖(SSO)个体(体重指数>60kg/m)对减重外科医生来说是一个治疗挑战。

目的

比较腹腔镜袖状胃切除术(SG)和腹腔镜 Roux-en-Y 胃旁路术(RYGB)的长期结果,并评估 SG 作为 SSO 患者的独立减重手术的疗效。

地点

法国巴黎的一家大学医院。

方法

我们回顾性分析了 2000 年 1 月至 2011 年 12 月期间接受 SG 或 RYGB 的 210 例 SSO 患者的数据结果。分析并比较了 6 年的随访数据。

结果

SG 组和 RYGB 组分别有 57.1%和 52.1%的患者获得了 6 年的随访数据。两种手术都能有效地促进体重减轻。大多数体重减轻发生在 24 个月时,两种手术的效果相似。SG 与 RYGB 的平均超重百分比减轻和体重指数变化在 4 年随访时没有显著差异。除睡眠呼吸暂停外,RYGB 对评估的合并症的缓解效果略好。RYGB 组有 11.7%的患者发生 30 天内主要短期不良事件,SG 组有 6.4%(P=0.02)。RYGB 组的术后并发症发生率为 26%,SG 组为 16.1%。

结论

即使 RYGB 能获得更好的中期结果,SG 作为 SSO 患者的主要手术仍然有效。SG 可以作为首选手术方案。需要进一步研究来确定患有胃食管反流病症状的患者的理想手术方法。

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