液体活检：新型技术与临床应用。

Liquid biopsy: novel technologies and clinical applications.

机构信息

Department of Tumor Biology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.

Department of Tumor Biology, University Medical Centre Hamburg-Eppendorf, Martinistr. 52, Hamburg 20246, Germany.

出版信息

Clin Chem Lab Med. 2019 Feb 25;57(3):312-316. doi: 10.1515/cclm-2018-0610.

DOI:10.1515/cclm-2018-0610

PMID:30465714

Abstract

"Liquid biopsy" was introduced as a new diagnostic concept in 2010 for the analysis of circulating tumor cells (CTCs) and has been now extended to material (in particular DNA) released by tumor cells in the peripheral blood of cancer patients. Over the past decade, various methods have been developed to detect CTCs and ctDNA in the peripheral blood of cancer patients.

摘要

"液体活检"于 2010 年被引入作为一种新的诊断概念，用于分析循环肿瘤细胞（CTC），现在已经扩展到分析肿瘤细胞在癌症患者外周血中释放的物质（特别是 DNA）。在过去的十年中，已经开发出各种方法来检测癌症患者外周血中的 CTC 和 ctDNA。