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液体活检:病理学的一条新途径。

Liquid biopsy: A new avenue in pathology.

作者信息

Ghosh Ratan Kumar, Pandey Tushar, Dey Pranab

机构信息

Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Department of Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Cytopathology. 2019 Mar;30(2):138-143. doi: 10.1111/cyt.12661. Epub 2019 Jan 11.

Abstract

Liquid biopsy is a relatively new entity. This non-invasive technique provides real-time information about a tumour. The liquid biopsy contains circulating tumour cells, cell-free DNA and exosomes. The main indications for liquid biopsy include early diagnosis, screening, detection of minimal residual disease, designing personalised treatment and predicting biological behaviour of the tumour. In this review, we discuss various aspects of liquid biopsy and compare it with conventional biopsy.

摘要

液体活检是一个相对较新的领域。这种非侵入性技术可提供有关肿瘤的实时信息。液体活检包含循环肿瘤细胞、游离DNA和外泌体。液体活检的主要适应证包括早期诊断、筛查、检测微小残留病、设计个性化治疗方案以及预测肿瘤的生物学行为。在本综述中,我们讨论了液体活检的各个方面,并将其与传统活检进行比较。

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