骨髓来源的干细胞有助于子宫内膜的再生。
Bone marrow-derived stem cells contribute to regeneration of the endometrium.
作者信息
Lee Youn Jeong, Yi Kyong Wook
机构信息
Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, Korea.
出版信息
Clin Exp Reprod Med. 2018 Dec;45(4):149-153. doi: 10.5653/cerm.2018.45.4.149. Epub 2018 Nov 30.
Abstract
Stem cells are undifferentiated cells capable of self-renewal and differentiation into various cell lineages. Stem cells are responsible for the development of organs and regeneration of damaged tissues. The highly regenerative nature of the human endometrium during reproductive age suggests that stem cells play a critical role in endometrial physiology. Bone marrow-derived cells migrate to the uterus and participate in the healing and restoration of functionally or structurally damaged endometrium. This review summarizes recent research into the potential therapeutic effects of bone marrow-derived stem cells in conditions involving endometrial impairment.
摘要
干细胞是能够自我更新并分化为各种细胞谱系的未分化细胞。干细胞负责器官的发育和受损组织的再生。育龄期女性子宫内膜具有高度再生能力，这表明干细胞在子宫内膜生理学中起着关键作用。骨髓来源的细胞迁移至子宫，参与功能或结构受损的子宫内膜的愈合与修复。本综述总结了近期关于骨髓来源干细胞在子宫内膜损伤相关病症中潜在治疗作用的研究。
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