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L-carnitine does not ameliorate asparaginase-associated hepatotoxicity in a C57BL6 mouse model.

作者信息

Liu Yiwei, Janke Laura J, Li Lie, Relling Mary V

机构信息

a Department of Pharmaceutical Sciences , St. Jude Children's Research Hospital , Memphis , TN , USA.

b Department of Pathology , St. Jude Children's Research Hospital , Memphis , TN , USA.

出版信息

Leuk Lymphoma. 2019 Aug;60(8):2088-2090. doi: 10.1080/10428194.2019.1571198. Epub 2019 Feb 4.

Abstract
摘要

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本文引用的文献

1
Levocarnitine for asparaginase-induced hepatic injury: a multi-institutional case series and review of the literature.
Leuk Lymphoma. 2018 Oct;59(10):2360-2368. doi: 10.1080/10428194.2018.1435873. Epub 2018 Feb 12.
2
Levocarnitine and vitamin B complex for the treatment of pegaspargase-induced hepatotoxicity: A case report and review of the literature.
J Oncol Pharm Pract. 2018 Jul;24(5):393-397. doi: 10.1177/1078155217710714. Epub 2017 May 19.
4
Genome-Wide Study Links PNPLA3 Variant With Elevated Hepatic Transaminase After Acute Lymphoblastic Leukemia Therapy.
Clin Pharmacol Ther. 2017 Jul;102(1):131-140. doi: 10.1002/cpt.629. Epub 2017 Apr 4.
7
L-Carnitine for Treatment of Pegasparaginase-Induced Hepatotoxicity.
Acta Haematol. 2016;135(4):208-10. doi: 10.1159/000442342. Epub 2016 Feb 4.
8
Successful treatment of pegaspargase-induced acute hepatotoxicity with vitamin B complex and L-carnitine.
Proc (Bayl Univ Med Cent). 2016 Jan;29(1):46-7. doi: 10.1080/08998280.2016.11929355.
10
Investigation of protective effect of L-carnitine on L-asparaginase-induced acute pancreatic injury in male Balb/c mice.
Dig Dis Sci. 2015 May;60(5):1290-6. doi: 10.1007/s10620-014-3461-3. Epub 2014 Dec 14.

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