冷遇型养育与后代细胞衰老有关：一项回顾性研究。
Cold parenting is associated with cellular aging in offspring: A retrospective study.
机构信息
Center for Nutrition, Healthy Lifestyle and Disease Prevention, School of Public Health, Loma Linda University, Loma Linda, CA 92350, United States.
Department of Basic Science, School of Medicine, Loma Linda University, Loma Linda, CA 92350, United States.
出版信息
Biol Psychol. 2019 Jul;145:142-149. doi: 10.1016/j.biopsycho.2019.03.013. Epub 2019 Apr 20.
BACKGROUND
Early life stress is a known risk factor for diseases and premature death. We tested whether parenting style impacts telomere length (TL), a cellular aging biomarker.
METHODS
Information on parents' style of parenting was obtained from 199 participants in the Adventist Health Study-1 (AHS-1) who 27+ years later also enrolled in the AHS-2 where blood was collected for relative TL (rTL) assessment.
RESULTS
Subjects describing their mothers' parenting style as cold had on average 25% smaller rTL compared to subjects not reporting a cold mother (1.89 vs 2.53). This association was greatest among those with less education, and those who stayed overweight/obese or put on weight during follow-up.
CONCLUSIONS
These results support previous findings that early life stress may have health implications by promoting cellular aging, and expands these stressors to include cold parenting during an individuals' formative years. Higher education and normal weight seem to provide some resilience.
背景
早期生活压力是疾病和早逝的已知风险因素。我们检验了父母教养方式是否会影响端粒长度（TL），这是一种细胞衰老生物标志物。
方法
199 名参加 Adventist Health Study-1（AHS-1）的参与者提供了有关其父母教养方式的信息，27 年后他们也参加了 Adventist Health Study-2，在该研究中采集了血液以评估相对端粒长度（rTL）。
结果
与未报告冷漠母亲的参与者相比，描述其母亲教养方式冷漠的参与者的 rTL 平均小 25%（1.89 与 2.53）。这种关联在受教育程度较低的人群以及在随访期间体重超重/肥胖或体重增加的人群中最为明显。
结论
这些结果支持了早期生活压力可能通过促进细胞衰老对健康产生影响的先前发现，并将这些压力源扩展到个体成长过程中的冷漠养育。较高的教育程度和正常体重似乎提供了一些韧性。
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