Department of Internal Medicine and Clinical Nutrition, Krefting Research Centre, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Wallenberg Center for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.
Allergy. 2019 Sep;74(9):1703-1715. doi: 10.1111/all.13840. Epub 2019 Jul 1.
Asthma is a common chronic inflammatory disease of the airways, with a noticeable increase in prevalence during the second half of the 20th century. Recent studies assessing the prevalence trends among adults have been inconsistent. We investigated the changes in the prevalence of asthma, respiratory symptoms, and risk factors between 2008 and 2016 in western Sweden.
The West Sweden Asthma Study (WSAS) is a population-based study which started in 2008 (WSAS I) and then repeated in 2016 (WSAS II) in western Sweden. Randomly selected individuals aged 16-75 years (N = 18 087 in 2008 and N = 24 534 in 2016) completed a questionnaire regarding obstructive lung diseases, respiratory symptoms, potential risk factors, and also questions from the GA LEN survey.
The prevalence of reported ever asthma, physician-diagnosed asthma, use of asthma medication, and current asthma increased significantly from 9.6% to 11%, 8.3% to 10%, 8.6% to 9.8%, and 8.1% to 9.1%, respectively, between 2008 and 2016. There were also increases in the prevalence of respiratory symptoms during the same period. The greatest increase occurred in young adults aged 16-25 years. Female gender, allergic rhinitis, obesity, and family history of asthma remained the strongest risk factors for asthma in 2016 as it was in 2008.
There were moderate increases in asthma and respiratory symptoms in adults in western Sweden between 2008 and 2016, the greatest increase occurring in younger adults. The potential risk factors for asthma remained the same during the study period.
哮喘是一种常见的气道慢性炎症性疾病,其在 20 世纪后半叶的发病率显著增加。最近评估成年人患病率趋势的研究结果并不一致。我们调查了 2008 年至 2016 年在瑞典西部哮喘、呼吸道症状和危险因素的患病率变化。
西瑞典哮喘研究(WSAS)是一项基于人群的研究,于 2008 年(WSAS I)首次开展,随后于 2016 年(WSAS II)在瑞典西部再次开展。随机选择年龄在 16-75 岁之间的个体(2008 年为 18087 人,2016 年为 24534 人)完成一份关于阻塞性肺部疾病、呼吸道症状、潜在危险因素的调查问卷,以及来自 GA LEN 调查的问题。
报告的既往哮喘、医生诊断的哮喘、使用哮喘药物和当前哮喘的患病率从 2008 年的 9.6%、8.3%、8.6%和 8.1%显著增加到 2016 年的 11%、10%、9.8%和 9.1%。在此期间,呼吸道症状的患病率也有所增加。最大的增长发生在 16-25 岁的年轻成年人中。女性、过敏性鼻炎、肥胖和哮喘家族史在 2016 年和 2008 年一样,仍然是哮喘的最强危险因素。
在 2008 年至 2016 年期间,瑞典西部成年人的哮喘和呼吸道症状中度增加,年轻成年人的增幅最大。在研究期间,哮喘的潜在危险因素保持不变。