Addiction and Dual Diagnosis Unit, Hospital Universitari Vall d'Hebron Spain; Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Spain; Biomedical Network Research Centre on Mental Health (CIBERSAM), Spain.
Addiction and Dual Diagnosis Unit, Hospital Universitari Vall d'Hebron Spain; Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Spain; Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Spain; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Catalonia, Spain.
Psychiatry Res. 2019 Jun;276:283-289. doi: 10.1016/j.psychres.2019.05.026. Epub 2019 May 16.
Psychiatric comorbidity can negatively impact the course of addictions. Psychiatric features of patients who continued treatment after the first stage of an addiction program have not been sufficiently analysed. Therefore, only these patients were included in order to compare psychiatric comorbidity and clinical factors between patients who were able or not to complete a long term substance-free program. Treatment-completion status of 245 patients was systematically recorded. Addiction severity, psychiatry comorbidity, and psychological symptoms were evaluated. No significant differences were found regarding comorbid psychiatric diagnoses and the completion of the treatment. Longer treatment duration (OR: 1.22; p < 0.01), higher educational level (OR: 2.37; p = 0.02), and cocaine dependence as main substance (OR: 3.68; p < 0.01) were found to be related to increased likelihood in completing the treatment. Patients with higher severity of alcohol consumption (OR: 0.06; p = 0.02) and more depressive symptoms (OR: 0.95; p = 0.01) completed the treatment less frequently. Moreover, differences regarding employment problems, treatment facilities, anxiety symptoms, dysfunctional impulsivity, and mental HRQoL were found. It is concluded that comorbid psychiatric diagnoses do not determine treatment outcomes. However, therapeutic and psychological factors have a major influence on the likelihood to complete a long-term treatment program.
精神共病会对成瘾的病程产生负面影响。对于在成瘾项目第一阶段后继续治疗的患者的精神特征,尚未进行充分分析。因此,仅纳入这些患者,以比较能够或不能完成长期无物质滥用计划的患者之间的精神共病和临床因素。系统地记录了 245 名患者的治疗完成情况。评估了成瘾严重程度、精神共病和心理症状。在共病精神诊断和治疗完成方面未发现显著差异。更长的治疗持续时间(OR:1.22;p < 0.01)、更高的教育水平(OR:2.37;p = 0.02)和可卡因依赖作为主要物质(OR:3.68;p < 0.01)与增加治疗完成的可能性相关。酒精消耗严重程度较高的患者(OR:0.06;p = 0.02)和抑郁症状较多的患者(OR:0.95;p = 0.01)完成治疗的频率较低。此外,还发现了与就业问题、治疗设施、焦虑症状、功能失调冲动和心理健康 HRQoL 相关的差异。结论是,精神共病诊断并不能决定治疗结果。然而,治疗和心理因素对完成长期治疗计划的可能性有重大影响。