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尼日利亚拉各斯家禽养殖场分离菌株的抗生素敏感性分析——一项初步研究

Antibiotic Susceptibility Profiles of Isolated from Poultry Farms in Lagos Nigeria - A Pilot Study.

作者信息

Ogbor Oreva, Ajayi Abraham, Zautner Andreas E, Smith Stella I

机构信息

Department of Microbiology, University of Lagos Akoka, Nigeria.

Department of Medical Microbiology, University Medical Center Göttingen, Germany.

出版信息

Eur J Microbiol Immunol (Bp). 2019 May 21;9(2):32-34. doi: 10.1556/1886.2019.00007. eCollection 2019 Jun 3.

Abstract

and are among the leading causes of gastroenteritis in humans worldwide, particularly in Africa. Poultry remains a major source of species and a vector of transmission to humans. This pilot study was aimed at isolating and determining the antibiotic susceptibility profiles of spp. from fresh poultry droppings collected from poultry farms in Lagos State, Nigeria. Susceptibility was assessed using the CLSI standards. Standard microbiological methods were used in isolation, identification, and characterization of spp. Isolates were subjected to antibiotic susceptibility testing by the disk diffusion method. Of the 150 poultry droppings analyzed, 8 (5.3%) harbored All isolates proved to be since they were all negative for the gene. A percentage of 100% showed resistance to nalidixic acid, chloramphenicol, cloxacillin, and streptomycin. While 87.5% were susceptible to amoxicillin and amoxicillin/clavulanic acid, 62.5% were susceptible to tetracycline. Surprisingly, 62.5% of had decreased (intermediate) susceptibility to erythromycin. Although there was a low prevalence of from poultry in this study, the presence of antibiotic resistant strains circulating the food chain could result in treatment failures and difficulty in case management if involved in infections of humans.

摘要

[具体细菌名称]和[具体细菌名称]是全球人类肠胃炎的主要病因,在非洲尤为如此。家禽仍然是[具体细菌名称]物种的主要来源以及传播给人类的媒介。这项初步研究旨在从尼日利亚拉各斯州家禽养殖场收集的新鲜家禽粪便中分离并确定[具体细菌名称]菌株的抗生素敏感性概况。使用美国临床和实验室标准协会(CLSI)标准评估敏感性。采用标准微生物学方法对[具体细菌名称]菌株进行分离、鉴定和特征描述。通过纸片扩散法对分离株进行抗生素敏感性测试。在分析的150份家禽粪便中,8份(5.3%)含有[具体细菌名称]。所有分离株均被证明是[具体情况],因为它们的[具体基因]均为阴性。100%的分离株对萘啶酸、氯霉素、氯唑西林和链霉素表现出耐药性。虽然87.5%的分离株对阿莫西林和阿莫西林/克拉维酸敏感,但62.5%的分离株对四环素敏感。令人惊讶的是,62.5%的[具体细菌名称]对红霉素的敏感性降低(处于中介水平)。尽管本研究中家禽携带[具体细菌名称]的患病率较低,但如果涉及人类感染,食物链中循环的抗生素耐药菌株的存在可能导致治疗失败和病例管理困难。

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