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考察薄荷醇香烟在青少年向已确立的吸烟习惯发展中的作用。

Examining the role of menthol cigarettes in progression to established smoking among youth.

机构信息

RTI International, 3040 E. Cornwallis Road, P.O. Box 12194, Research Triangle Park, NC 27709, United States of America.

Office of Science, Center for Tobacco Products, Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD 20993, United States of America.

出版信息

Addict Behav. 2019 Nov;98:106045. doi: 10.1016/j.addbeh.2019.106045. Epub 2019 Jul 5.

Abstract

BACKGROUND

Menthol, a flavoring compound added to cigarettes, makes cigarettes more appealing to youth and inexperienced smokers and increases cigarettes' abuse liability. However, limited studies are available on menthol's role in smoking progression.

METHODS

To assess the association between menthol in cigarettes and progression to established smoking, we used five waves of data from the Evaluation of Public Education Campaign on Teen Tobacco Cohort Study, a nationally representative longitudinal survey of U.S. youth conducted as part of "The Real Cost" evaluation. We used discrete time survival analysis to model the occurrence of two event outcomes-progression to established, current smoking and progression to established, frequent smoking-using a logit model with a menthol use indicator as the key explanatory variable. Based on this framework, we estimated the effect of prior menthol use on the odds of smoking progression.

RESULTS

In the progression to established, current smoking model, prior menthol use was significantly associated with progression [adjusted odds ratio (aOR) = 1.80, p < .05, confidence interval (CI) = (1.03-3.16)]. While results were in a similar direction for the model of progression to established, frequent smoking, the association between prior menthol use and this progression model did not reach significance [aOR = 1.56, CI = (0.80-3.03)].

CONCLUSION

The results suggest a relationship between using menthol cigarettes and progression from experimental to established, current smoking among youth. This study adds to a growing literature base that supports that menthol cigarettes, compared to nonmenthol cigarettes, put youth at increased risk for regular cigarette use.

摘要

背景

薄荷醇是一种添加到香烟中的调味化合物,它使香烟对年轻人和经验不足的吸烟者更具吸引力,并增加了香烟的滥用可能性。然而,关于薄荷醇在吸烟进展中的作用的研究有限。

方法

为了评估香烟中薄荷醇与已确立吸烟进展之间的关联,我们使用了“青少年烟草队列研究”的公共教育运动评估中的五个波次的数据,这是一项对美国青少年进行的全国代表性纵向调查,作为“真实成本”评估的一部分。我们使用离散时间生存分析,使用逻辑模型作为关键解释变量,使用 logit 模型对两个事件结果(向已确立的当前吸烟和向已确立的频繁吸烟的进展)的发生进行建模。基于这一框架,我们估计了以前使用薄荷醇对吸烟进展可能性的影响。

结果

在向已确立的当前吸烟模型中,以前使用薄荷醇与吸烟进展显著相关[调整后的优势比 (aOR) = 1.80,p < .05,置信区间 (CI) = (1.03-3.16)]。虽然在向已确立的频繁吸烟模型中结果的方向相似,但以前使用薄荷醇与这一进展模型之间的关联没有达到显著性[aOR = 1.56,CI = (0.80-3.03)]。

结论

结果表明,使用薄荷醇香烟与年轻人从实验性吸烟向已确立的当前吸烟的进展之间存在关系。这项研究增加了越来越多的文献基础,支持薄荷醇香烟与非薄荷醇香烟相比,使年轻人更有可能经常使用香烟。

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