Department of Ophthalmology, Shanghai First People's Hospital, School of Medicine, Shanghai JiaoTong University, Shanghai, China.
Shanghai Key Laboratory of Fundus Disease, Shanghai, China.
Curr Eye Res. 2020 Jan;45(1):31-37. doi: 10.1080/02713683.2019.1649703. Epub 2019 Aug 12.
: To evaluate the short-term influence of uncomplicated phacoemulsification on fundus structure and vasculature change.: A total of 51 eyes from 51 patients with mild-to-moderate cataracts were included. Retinal vessel density, perfusion density, and layer thickness in both macular and peripapillary areas were scanned by OCT at baseline and at 1 day, 1 week, and 1 month after cataract surgery. Cumulative dissipated energy (CDE), U/S total time (USTT) and total aspiration time (TAT) were recorded as parameters of surgical injury to analyze the surgical influence on fundus change.: There was a significant increase up in retinal vasculature parameters in both macular and optic nerve area after the surgery. The retinal layer thickness had pronounced increase from 1 week after the surgery (all < .05, repeated-measures analysis of variance). Retinal nerve fiber layer (RNFL) thickness and ganglion cell layer (GCL) thickness increased more rapidly than other layers. There was a positive correlation between CDE and vasculature changes from 1 week to 1 month (Vessel density in macular to CDE: standardized β = 0.448, = .005; Perfusion density in peripapillary area to CDE: standardized β = 0.382, = .015).: Retinal vasculature and layer thickness increased in short-term follow-up after cataract surgery. Whether these changes would persist over a longer period needs to be verified.
: 评估单纯性白内障超声乳化术对眼底结构和血管变化的短期影响。
: 共纳入 51 例轻中度白内障患者的 51 只眼。在白内障手术后 1 天、1 周和 1 个月,用 OCT 扫描黄斑区和视盘周围视网膜血管密度、灌注密度和层厚。记录累积耗散能量(CDE)、超声总时间(USTT)和总抽吸时间(TAT)作为手术损伤的参数,分析手术对眼底变化的影响。
: 术后黄斑区和视神经区视网膜血管参数均显著增加。术后 1 周,视网膜层厚明显增加(均 <.05,重复测量方差分析)。视网膜神经纤维层(RNFL)和节细胞层(GCL)厚度增加较其他层更快。从术后 1 周到 1 个月,CDE 与血管变化呈正相关(黄斑区血管密度与 CDE:标准化β=0.448,=.005;视盘周围区灌注密度与 CDE:标准化β=0.382,=.015)。
: 白内障手术后短期随访中视网膜血管和层厚增加。这些变化是否会持续更长时间需要进一步验证。