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白内障超声乳化术后视网膜血管和层厚度的短期变化。

Short-Term Changes in Retinal Vasculature and Layer Thickness after Phacoemulsification Surgery.

机构信息

Department of Ophthalmology, Shanghai First People's Hospital, School of Medicine, Shanghai JiaoTong University, Shanghai, China.

Shanghai Key Laboratory of Fundus Disease, Shanghai, China.

出版信息

Curr Eye Res. 2020 Jan;45(1):31-37. doi: 10.1080/02713683.2019.1649703. Epub 2019 Aug 12.

Abstract

: To evaluate the short-term influence of uncomplicated phacoemulsification on fundus structure and vasculature change.: A total of 51 eyes from 51 patients with mild-to-moderate cataracts were included. Retinal vessel density, perfusion density, and layer thickness in both macular and peripapillary areas were scanned by OCT at baseline and at 1 day, 1 week, and 1 month after cataract surgery. Cumulative dissipated energy (CDE), U/S total time (USTT) and total aspiration time (TAT) were recorded as parameters of surgical injury to analyze the surgical influence on fundus change.: There was a significant increase up in retinal vasculature parameters in both macular and optic nerve area after the surgery. The retinal layer thickness had pronounced increase from 1 week after the surgery (all < .05, repeated-measures analysis of variance). Retinal nerve fiber layer (RNFL) thickness and ganglion cell layer (GCL) thickness increased more rapidly than other layers. There was a positive correlation between CDE and vasculature changes from 1 week to 1 month (Vessel density in macular to CDE: standardized β = 0.448, = .005; Perfusion density in peripapillary area to CDE: standardized β = 0.382, = .015).: Retinal vasculature and layer thickness increased in short-term follow-up after cataract surgery. Whether these changes would persist over a longer period needs to be verified.

摘要

: 评估单纯性白内障超声乳化术对眼底结构和血管变化的短期影响。

: 共纳入 51 例轻中度白内障患者的 51 只眼。在白内障手术后 1 天、1 周和 1 个月,用 OCT 扫描黄斑区和视盘周围视网膜血管密度、灌注密度和层厚。记录累积耗散能量(CDE)、超声总时间(USTT)和总抽吸时间(TAT)作为手术损伤的参数,分析手术对眼底变化的影响。

: 术后黄斑区和视神经区视网膜血管参数均显著增加。术后 1 周,视网膜层厚明显增加(均 <.05,重复测量方差分析)。视网膜神经纤维层(RNFL)和节细胞层(GCL)厚度增加较其他层更快。从术后 1 周到 1 个月,CDE 与血管变化呈正相关(黄斑区血管密度与 CDE:标准化β=0.448,=.005;视盘周围区灌注密度与 CDE:标准化β=0.382,=.015)。

: 白内障手术后短期随访中视网膜血管和层厚增加。这些变化是否会持续更长时间需要进一步验证。

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