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坦桑尼亚失学青少年女孩和年轻妇女中抑郁和焦虑症状的流行情况及其相关因素:一项横断面研究。

Prevalence and correlates of depression and anxiety symptoms among out-of-school adolescent girls and young women in Tanzania: A cross-sectional study.

机构信息

Department of Sexual and Reproductive Health, National Institute for Medical Research, Mwanza, Tanzania.

Sauti Project, Jhpiego Tanzania-an affiliate of Johns Hopkins University, Dar es Salaam, Tanzania.

出版信息

PLoS One. 2019 Aug 16;14(8):e0221053. doi: 10.1371/journal.pone.0221053. eCollection 2019.

Abstract

BACKGROUND

In sub-Saharan Africa, adolescent girls and young women (AGYW) who are out of school are at higher risk of depressive and anxiety disorders compared to their school attending peers. However, little is known about the prevalence and risk factors for these conditions among out-of-school AGYW. This study examines the prevalence of depression and anxiety and associated factors in a community sample of out-of-school AGYW in Tanzania.

METHODS

A cross-sectional analysis of baseline data from an on-going cluster randomized controlled trial in North-West Tanzania was conducted. A total of 3013 out-of-school AGYW aged 15 to 23 years from 30 clusters were included. Anxiety and depression were assessed using the Patient Health Questionnaire (PHQ-4), a tool comprising of PHQ-2 and Generalized Anxiety Disorders (GAD-2) screeners. Data were collected using Audio Computer-Assisted Self-Interview (ACASI). A random-effects logistic regression was fitted for binary outcomes and an ordinal logistic regression model with robust variance was used to adjust for clustering at the village level. Logistic regression and ordinal logistic regression were used to explore the associations between mental disorders symptoms and other factors.

RESULTS

The prevalence of depressive (PHQ-2 ≥ 3) and anxiety (GAD-2 ≥ 3) symptoms among out-of-school AGYW were 36% (95% CI 33.8%-37.3%) and 31% (95% CI 29.0%-32.3%) respectively. Further, using the PHQ-4 tool, 33% (95% CI 30.8%-34.2%) had mild, 20% (95% CI 18.3%-21.1%) moderate and 6% (95% CI 5.5%-7.2%) had severe symptoms of anxiety and depression. After adjusting for other covariates, two factors most strongly associated with having anxiety symptoms were violence experience from sexual partners (AOR = 1.63, 95% CI: 1.36-1.96) and HIV positive status (AOR = 1.54, 95% CI: 1.03-2.31). Likewise, living alone, with younger siblings or others (AOR = 2.51, 95% CI: 1.47-4.29) and violence experience from sexual partners (AOR = 1.90, 95% CI: 1.59-2.27) were strongly associated with depression symptoms. Having savings (AOR = 0.81, 95% CI: 0.70-0.95) and emotional support (AOR = 0.82, 95% CI: 0.67-0.99) were protective against depression and anxiety, respectively.

CONCLUSION

Depressive and anxiety symptoms are prevalent among out-of-school AGYW in Tanzania. The findings emphasize the need to strengthen preventive interventions and scale-up mental health disorder screening, referral for diagnosis and management.

摘要

背景

在撒哈拉以南非洲地区,失学的青少年女孩和年轻女性(AGYW)比在校同龄人更容易患上抑郁和焦虑障碍。然而,对于失学的 AGYW 中这些疾病的患病率和风险因素知之甚少。本研究旨在检查坦桑尼亚社区中失学的 AGYW 中抑郁和焦虑的患病率及其相关因素。

方法

对坦桑尼亚西北部正在进行的一项基于群组的随机对照试验的基线数据进行了横断面分析。共纳入了来自 30 个群组的 3013 名年龄在 15 至 23 岁之间的失学 AGYW。使用患者健康问卷(PHQ-4)评估焦虑和抑郁,该工具包括 PHQ-2 和广泛性焦虑症(GAD-2)筛查器。使用音频计算机辅助自我访谈(ACASI)收集数据。对于二项结果,使用随机效应逻辑回归进行拟合,对于聚类在村庄层面的情况,使用稳健方差的有序逻辑回归模型进行调整。使用逻辑回归和有序逻辑回归探索精神障碍症状与其他因素之间的关联。

结果

失学的 AGYW 中,抑郁(PHQ-2≥3)和焦虑(GAD-2≥3)症状的患病率分别为 36%(95%CI 33.8%-37.3%)和 31%(95%CI 29.0%-32.3%)。此外,使用 PHQ-4 工具,33%(95%CI 30.8%-34.2%)有轻度、20%(95%CI 18.3%-21.1%)有中度和 6%(95%CI 5.5%-7.2%)有重度焦虑和抑郁症状。在校正其他协变量后,与焦虑症状最相关的两个因素是性伴侣的暴力经历(AOR=1.63,95%CI:1.36-1.96)和 HIV 阳性状态(AOR=1.54,95%CI:1.03-2.31)。同样,独居、与年幼的兄弟姐妹或其他人同住(AOR=2.51,95%CI:1.47-4.29)和性伴侣的暴力经历(AOR=1.90,95%CI:1.59-2.27)与抑郁症状密切相关。有储蓄(AOR=0.81,95%CI:0.70-0.95)和情感支持(AOR=0.82,95%CI:0.67-0.99)分别对抑郁和焦虑具有保护作用。

结论

坦桑尼亚失学的 AGYW 中存在抑郁和焦虑症状。研究结果强调需要加强预防干预措施,并扩大精神障碍筛查、诊断和管理服务。

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