Gautam Nischal K, Bober Kayla, Pierre James A, Pawelek Olga, Griffin Evelyn
University of Texas Health, Houston, TX, USA.
Semin Cardiothorac Vasc Anesth. 2019 Dec;23(4):387-392. doi: 10.1177/1089253219870628. Epub 2019 Aug 20.
. Deep tracheal extubation using dexmedetomidine is safe and provides smooth recovery in children with congenital heart disease undergoing cardiac catheterization. . Single-institution, retrospective study of prospectively collected data. . All patients aged between 1 month and 5 years who underwent general endotracheal anesthesia for diagnostic and interventional cardiac catheterizations in the cardiac catheterization suite from January 2015 (change in standard operating procedure) through October 2016 (approval of institutional review board for study). . One hundred and eighty-nine patients (81%) of the 232 patients who underwent cardiac catheterization during the study period were noted to undergo deep tracheal extubation. Cyanotic heart disease was present in 87 patients (46%), history of prematurity in 51 (27%), and pulmonary hypertension in 26 (14%) patients. A documented smooth recovery in the postoperative care unit (PACU) requiring no additional analgesics or sedatives was observed in 91% of the patients. The majority of patients required no airway support after deep extubation (n = 140, 74%, = .136). The presence of pulmonary hypertension (odds ratio = 4.45, = .035) and presence of a cough on the day of the procedure (odds ratio = 7.10, = .03) were significantly associated with the use of oxygen or use of oral airway for greater than 20 minutes in the PACU. After extubation, there were no reported events of aspiration, the use of noninvasive positive pressure ventilation, reintubation, heart block, or systemic hypotension requiring treatment or cardiac arrest. . Deep extubation using dexmedetomidine in infants and toddlers after cardiac catheterization is feasible and enables smooth postoperative recovery with minimal adverse effects.
使用右美托咪定进行深度气管拔管对接受心导管插入术的先天性心脏病患儿是安全的,并能使其平稳恢复。
对前瞻性收集的数据进行单机构回顾性研究。
纳入2015年1月(标准操作程序变更)至2016年10月(机构审查委员会批准该研究)期间在心脏导管插入室接受全身气管内麻醉进行诊断性和介入性心导管插入术的所有1个月至5岁的患者。
在研究期间接受心导管插入术的232例患者中,有189例(81%)进行了深度气管拔管。其中87例(46%)患有青紫型心脏病,51例(27%)有早产史,26例(14%)有肺动脉高压。91%的患者在术后护理单元(PACU)恢复平稳,无需额外使用镇痛药或镇静剂。大多数患者在深度拔管后无需气道支持(n = 140,74%,P = 0.136)。肺动脉高压(优势比 = 4.45,P = 0.035)和手术当天咳嗽(优势比 = 7.10,P = 0.03)与在PACU中使用氧气或使用口咽气道超过20分钟显著相关。拔管后,未报告有吸入、使用无创正压通气、重新插管、心脏传导阻滞或需要治疗的系统性低血压或心脏骤停事件。
对婴幼儿在心导管插入术后使用右美托咪定进行深度拔管是可行的,能使术后平稳恢复且不良反应最小。