Department of Animal Nutrition, West Bengal University of Animal and Fishery Sciences, 37 K.B. Sarani, Belgachia, Kolkata, 700037, India.
National Dairy Research Institute, Eastern Regional Station, Kalyani, West Bengal, India.
Biol Trace Elem Res. 2020 Sep;197(1):233-253. doi: 10.1007/s12011-019-01959-1. Epub 2019 Dec 12.
Nanobiotechnology is a growing field in animal and veterinary sciences for various practical applications including diagnostic, therapeutic, and nutritional applications. Recently, nanoforms or nanoparticles (NP) of essential minerals have been explored for growth performance, feed utilization, and health status of animals. Various mineral NP, such as calcium, zinc, copper, selenium, and chromium, have been studied in different farm animals including poultry. Because mineral NP are smaller in size, and show different chemical and physical properties, they are usually absorbed in greater amounts from gastrointestinal tract and exert enhanced biological effects in the target tissues of animals. In various studies, mineral NP have been comparatively studied relating to its larger inorganic and organic particles in poultry. There are contradictory findings among the studies on comparative improvement of production performance and other mineral functions perhaps due to different sizes, shapes, and properties of NP, and interactions of minerals present in basal diets. There are not many studies correlating physical and chemical properties of mineral NP and their biological functions in the body. Nonetheless, it appears that mineral NP have potential for their uses as mineral supplements in preference to inorganic mineral supplements for their better absorption avoiding antagonistic interactions with other minerals, growth performance, and physiological functions, especially at lower doses compared with the doses that are recommended for their larger particles. Supplementation of mineral NP in diets could be a promising option in the future. This review summarizes the studies of different essential mineral NP used as mineral supplements for feed intake, growth performance, egg production and quality, and blood variables in poultry.
纳米生物技术是动物学和兽医学领域的一个新兴领域,有各种实际应用,包括诊断、治疗和营养应用。最近,人们探索了必需矿物质的纳米形式或纳米颗粒 (NP),以提高动物的生长性能、饲料利用率和健康状况。各种矿物质 NP,如钙、锌、铜、硒和铬,已在不同的农场动物中进行了研究,包括家禽。由于矿物质 NP 的尺寸较小,并且表现出不同的化学和物理性质,因此它们通常从胃肠道中被更大量吸收,并在动物的靶组织中发挥增强的生物学效应。在各种研究中,已经比较了矿物质 NP 与其在家禽中的较大无机和有机颗粒的相关研究。由于 NP 的大小、形状和性质以及基础日粮中存在的矿物质的相互作用不同,因此关于生产性能和其他矿物质功能的比较改善的研究结果存在矛盾。目前还没有很多研究将矿物质 NP 的物理化学性质与其在体内的生物学功能相关联。尽管如此,矿物质 NP 似乎有可能作为矿物质补充剂替代无机矿物质补充剂,因为它们的吸收更好,避免了与其他矿物质的拮抗相互作用,从而提高了生长性能和生理功能,特别是与推荐剂量相比,在较低剂量下效果更好。在未来,在日粮中添加矿物质 NP 可能是一个很有前途的选择。本文综述了不同必需矿物质 NP 作为饲料摄入、生长性能、产蛋性能和质量以及家禽血液变量的补充剂的研究。