医院环境在多重耐药革兰氏阴性菌传播中的作用。
The role of hospital environment in transmissions of multidrug-resistant gram-negative organisms.
机构信息
National Centre for Infectious Diseases, Jln Tan Tock Seng, Singapore.
Department of Infectious Diseases, Tan Tock Seng Hospital, Block H, CHI Level 3, 18, Jalan Tan Tock Seng, 308442, Singapore.
出版信息
Antimicrob Resist Infect Control. 2020 Feb 11;9(1):29. doi: 10.1186/s13756-020-0685-1.
Abstract
Infections by multidrug-resistant (MDR) Gram-negative organisms (GN) are associated with a high mortality rate and present an increasing challenge to the healthcare system worldwide. In recent years, increasing evidence supports the association between the healthcare environment and transmission of MDRGN to patients and healthcare workers. To better understand the role of the environment in transmission and acquisition of MDRGN, we conducted a utilitarian review based on literature published from 2014 until 2019.
摘要
耐多药革兰氏阴性菌 (MDRGN) 感染与高死亡率相关，并且对全球医疗系统构成日益严峻的挑战。近年来，越来越多的证据支持医疗环境与 MDRGN 在患者和医护人员之间传播的关联。为了更好地了解环境在 MDRGN 传播和获得中的作用，我们对 2014 年至 2019 年发表的文献进行了实用主义综述。
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本文引用的文献
1
Bacteriological Assessment of the Indoor Air of Different Hospitals of Kathmandu District.
Int J Microbiol. 2019 Apr 8;2019:5320807. doi: 10.1155/2019/5320807. eCollection 2019.
2
Effect of carbapenem resistance on outcomes of bloodstream infection caused by Enterobacteriaceae in low-income and middle-income countries (PANORAMA): a multinational prospective cohort study.
Lancet Infect Dis. 2019 Jun;19(6):601-610. doi: 10.1016/S1473-3099(18)30792-8. Epub 2019 Apr 29.
3
Multidrug-resistant Organisms in Hospitals: What Is on Patient Hands and in Their Rooms?
Clin Infect Dis. 2019 Nov 13;69(11):1837-1844. doi: 10.1093/cid/ciz092.
4
Droplet aerosol dissemination of carbapenem-resistant Acinetobacter baumannii surrounding ventilated patients.
Infect Control Hosp Epidemiol. 2019 Mar;40(3):365-367. doi: 10.1017/ice.2018.335. Epub 2019 Feb 18.
5
Risk Assessment After a Severe Hospital-Acquired Infection Associated With Carbapenemase-Producing Pseudomonas aeruginosa.
JAMA Netw Open. 2019 Feb 1;2(2):e187665. doi: 10.1001/jamanetworkopen.2018.7665.
6
Dispersal of gram-negative bacilli from contaminated sink drains to cover gowns and hands during hand washing.
Infect Control Hosp Epidemiol. 2019 Apr;40(4):460-462. doi: 10.1017/ice.2019.25. Epub 2019 Feb 15.
7
A metallo-beta-lactamase producing Enterobacteriaceae outbreak from a contaminated tea dispenser at a children's hospital in Japan.
Infect Control Hosp Epidemiol. 2019 Feb;40(2):217-220. doi: 10.1017/ice.2018.331. Epub 2018 Dec 27.
8
Investigation of a Cluster of Sphingomonas koreensis Infections.
N Engl J Med. 2018 Dec 27;379(26):2529-2539. doi: 10.1056/NEJMoa1803238.
9
Acetic acid as a decontamination method for ICU sink drains colonized by carbapenemase-producing Enterobacteriaceae and its effect on CPE infections.
J Hosp Infect. 2019 May;102(1):82-88. doi: 10.1016/j.jhin.2018.12.009. Epub 2018 Dec 21.
10
Carbapenem-resistant Enterobacteriaceae dispersal from sinks is linked to drain position and drainage rates in a laboratory model system.
J Hosp Infect. 2019 May;102(1):63-69. doi: 10.1016/j.jhin.2018.12.007. Epub 2018 Dec 18.
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