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单中心腹腔镜根治性膀胱切除术后全内脏层回肠导管尿流改道术的手术结果和学习曲线。

Surgical outcomes and learning curve of totally intracorporeal ileal conduit urinary diversion following laparoscopic radical cystectomy at a single institution.

机构信息

Department of Urology, Kobe City Medical Centre General Hospital, Kobe, Japan.

出版信息

Asian J Endosc Surg. 2020 Oct;13(4):532-538. doi: 10.1111/ases.12793. Epub 2020 Feb 28.

Abstract

INTRODUCTION

Constant evaluation of the outcomes of laparoscopic intracorporeal urinary diversion is not yet established. This study aimed to describe surgical outcomes and learning curve of intracorporeal ileal conduit (ICIC) following laparoscopic radical cystectomy (LRC) at a single institution.

METHODS

From June 2012 to February 2018, 38 patients with bladder cancer underwent LRC with ileal conduit at our institution. Surgical outcomes were compared between ICIC (n = 30) and extracorporeal ileal conduit (ECIC) (n = 8). The learning curve during ICIC with regard to the operative time and complication rate was compared.

RESULTS

No significant differences in patient characteristics between the ICIC and ECIC groups were found. Comparison of outcomes between the ICIC and ECIC groups were as follows: median total operative time, 688 vs 713 minutes; urinary diversion time, 213 vs 192 minutes; and estimated blood loss, 450 vs 420 mL, respectively. The median time to walking and oral intake were similar in both groups. Rates of high-grade complications associated with urinary diversion (Clavien-Dindo grade ≥ III) were 3% in ICIC and 25% in ECIC. Although 25% of ECIC patients developed wound dehiscence (Clavien-Dindo grade IIIb), no patient in the ICIC group had postoperative wound infection. For the learning curve of ICIC (n = 30), urinary diversion time decreased significantly (27 minutes decrease per 10 cases, P = .02). Clavien-Dindo grade ≥ II complication did not occur after 20 cases.

CONCLUSIONS

LRC with ICIC could be performed safely with low incidence of severe wound infection compared with ECIC. The incidence and severity of complications also decreased with time.

摘要

简介

腹腔镜下尿流改道术的效果评估尚未达成共识。本研究旨在描述在单一机构中进行腹腔镜根治性膀胱切除术(LRC)后行腔内回肠导管(ICIC)的手术结果和学习曲线。

方法

2012 年 6 月至 2018 年 2 月,我院 38 例膀胱癌患者接受 LRC 加回肠导管术。比较 ICIC(n=30)和体外回肠导管(ECIC)(n=8)患者的手术结果。比较 ICIC 术中手术时间和并发症发生率的学习曲线。

结果

ICIC 和 ECIC 组患者的特征无显著差异。ICIC 和 ECIC 组的结果比较如下:总手术时间中位数分别为 688 分钟和 713 分钟;尿流改道术时间中位数分别为 213 分钟和 192 分钟;估计失血量中位数分别为 450 毫升和 420 毫升。两组患者的行走和口服摄入时间中位数相似。与尿流改道相关的高级别并发症(Clavien-Dindo 分级≥III)的发生率分别为 ICIC 组 3%和 ECIC 组 25%。尽管 ECIC 组 25%的患者发生切口裂开(Clavien-Dindo 分级 IIIb),但 ICIC 组无一例患者发生术后伤口感染。对于 ICIC 的学习曲线(n=30),尿流改道术时间显著下降(每 10 例减少 27 分钟,P=0.02)。20 例后未发生 Clavien-Dindo 分级≥II 并发症。

结论

与 ECIC 相比,LRC 联合 ICIC 可安全进行,严重伤口感染发生率较低。随着时间的推移,并发症的发生率和严重程度也有所降低。

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