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疼痛评估

Pain Assessment

作者信息

Stretanski Michael F., Stinocher Samuel, Grandhe Sundeep

机构信息

Midwestern University, Glendale, AZ

University of California, San Francisco | Central Valley Hospice Palliative Medicine

Abstract

Pain management clinicians across specialties recognize the impossibility of directly measuring pain or suffering in another person. However, this limitation does not eliminate the need for objective measures or their approximations. Pain is the most common complaint in primary care. More than 50 million individuals in the United States (US)—approximately 20% of the population—experience chronic pain, with prevalence increasing significantly among older adults. Amid rising opioid use disorder, logical and adequate pain treatment remains critical. This reality underscores the importance of adjunctive agents defined by the World Health Organization that may reduce opioid reliance and the need to measure pain alongside the effects of these therapies. Pain assessment requires distinguishing acute from chronic pain; severe pain persisting beyond 3 months generally qualifies as chronic. This distinction proves essential, as chronic pain often reflects central nervous system dysfunction rather than peripheral nociception. Maladaptive changes such as hyperalgesia and allodynia become more common. Affected tissues develop a hypertonic, ropy, and cold texture, with pain sensations shifting from sharp to dull and achy. How pain is assessed significantly influences patients’ long-term morbidity and mortality. Over 30% of patients report pain lasting longer than 6 months, highlighting the need for clinicians to employ multiple tools to characterize pain and improve symptom management accurately. Approximately 8% of adults and 6% of children experience chronic pain that substantially limits function and quality of life, with an overall 20.9% of adults in the US affected to some degree. Effective treatments differ among acute, chronic, centralized, and neuropathic pain types. Neuropathic pain affects roughly 10% of the US population and may respond better to serotonin-norepinephrine reuptake inhibitors, such as duloxetine, than to nonsteroidal anti-inflammatory drugs like ibuprofen in acute injuries. Chronic pain ranks among the leading causes of disability and lost productivity in the US, resulting in billions of dollars in economic losses. Standardized pain assessment tools offer an objective means of monitoring symptoms and recovery over time. An important aspect of pain assessment involves recognizing the impact of comorbidities and psychosocial factors that influence pain perception. Mood disorders exacerbate pain, and their treatment often leads to improvement in symptoms. A patient’s history of opioid dependence, intravenous drug use, sexual abuse, trauma, advanced age, chronic illness, and economic disparity also contributes to pain experiences. Cultural factors further influence the expression and response to pain. Ultimately, integrating standardized testing, physical examination, psychological factors, including thought and mood disorders and their impact on perception, secondary gain, abuse history, and the emotional dimensions of pain and treatment response exemplifies how medicine combines art with science. The Numeric Rating Scale (NRS) is a simple and widely used tool for quantifying pain intensity, where patients rate their pain from 0 (no pain) to 10 (worst possible pain). Despite its popularity, the NRS remains a crude and generic measure, lacking consistency and objective verification. This scale proves useful in certain contexts, such as assessing pain before and after sublingual nitroglycerin administration for cardiac angina, or evaluating simple fractures in older patients, where a pain rating of 4 may correlate with respiratory suppression. However, the NRS has limitations. For example, patients with myofascial pain or uncertain diagnoses who report extreme pain (eg, 10/10) despite stable vital signs and evidence of analgesic administration may raise concerns for drug-seeking behavior. In cases involving an “aggressive escort” or a quiet patient, clinicians should note the language used, avoid assumptions, and maintain vigilance. Oral medications should be administered under supervision to prevent “sharing” or diversion, as “pocketing” pills for later use or trafficking is common. The presence of an escort dominating communication warrants careful assessment for potential abuse or trafficking. The Visual Analogue Scale functions similarly to the NRS but may incorporate pictorial elements to assist patients who do not share the clinician’s language. This scale consists of a line with endpoints labeled “no pain” and “worst possible pain,” where patients mark their pain level. The score corresponds to the distance from “no pain” to the mark. The VAS shares the same limitations as the NRS. The Wong-Baker FACES Pain Rating Scale is designed for pediatric individuals who may be nonverbal in acute settings and can also be adapted for use with adults who have communication difficulties. (Source: Wong Baker FACES History, 2016) The Nonverbal Pain Scale is particularly useful in intensive care units to assess pain in nonverbal adults, such as intubated but not fully sedated patients. The Behavioral Pain Scale offers an observational method for assessing pain in patients who are sedated or unconscious. This tool evaluates facial expressions, upper limb movements, and compliance with mechanical ventilation. Effective use requires considerable experience and interpretation within the clinical context, including the interpretation of vital signs. For example, tachycardia may indicate distress or resolution, depending on the patient’s medication, such as β-blockers or calcium channel blockers, which are commonly used among patients in the intensive care unit, regardless of ventilation status. The Short Form Health Survey 36 consists of 36 questions assessing multiple health domains, including physical functioning, role limitations, bodily pain, general health, vitality, social functioning, emotional role, and mental health. Although not solely a pain assessment tool, it serves as an objective measure of quality of life in patients with chronic pain. This tool may be used to guide chronic treatment decisions. Opinions vary regarding its utility across different populations. The common “squeeze my hand where it hurts most” technique is the worst tool. The McGill Pain Questionnaire (MPQ) is a self-reported instrument designed to assess both the quality and intensity of pain. This questionnaire presents 78 descriptors divided into sensory, affective, and evaluative categories, allowing patients to select words that best characterize their pain experience. The MPQ provides a quantitative measure useful for tracking pain over time and evaluating treatment effectiveness. The value of the MPQ lies in differentiating emotional-somatic descriptors such as “agonizing,” “dreadful,” and “torture” from sensory terms like “sharp,” “dull,” “throbbing,” or “constant.”

摘要

各个专业的疼痛管理临床医生都认识到,直接测量他人的疼痛或痛苦是不可能的。然而,这一局限性并不能消除对客观测量方法或其近似值的需求。疼痛是初级保健中最常见的主诉。在美国,超过5000万人(约占总人口的20%)经历慢性疼痛,且老年人中的患病率显著上升。在阿片类药物使用障碍不断增加的情况下,合理且充分的疼痛治疗仍然至关重要。这一现实凸显了世界卫生组织定义的辅助药物的重要性,这些药物可能会减少对阿片类药物的依赖,以及在测量疼痛的同时评估这些疗法效果的必要性。疼痛评估需要区分急性疼痛和慢性疼痛;持续超过3个月的严重疼痛通常可归类为慢性疼痛。这种区分至关重要,因为慢性疼痛往往反映中枢神经系统功能障碍而非外周伤害感受。痛觉过敏和异常性疼痛等适应不良变化变得更加常见。受影响的组织会出现高渗、条索状和冰冷的质地,疼痛感从尖锐变为钝痛和隐痛。疼痛评估的方式对患者的长期发病率和死亡率有显著影响。超过30%的患者报告疼痛持续超过6个月,这凸显了临床医生需要使用多种工具来准确描述疼痛并改善症状管理的必要性。大约8%的成年人和6%的儿童经历的慢性疼痛严重限制了功能和生活质量,美国总体上有20.9%的成年人在某种程度上受到影响。急性、慢性、中枢性和神经性疼痛类型的有效治疗方法各不相同。神经性疼痛影响约10%的美国人口,与急性损伤时使用布洛芬等非甾体抗炎药相比,使用度洛西汀等5-羟色胺-去甲肾上腺素再摄取抑制剂可能对其疗效更好。慢性疼痛是美国残疾和生产力损失的主要原因之一,造成了数十亿美元的经济损失。标准化的疼痛评估工具提供了一种客观手段,可用于监测症状和随时间的恢复情况。疼痛评估的一个重要方面是认识到合并症和心理社会因素对疼痛感知的影响。情绪障碍会加剧疼痛,对其进行治疗往往会使症状得到改善。患者的阿片类药物依赖史、静脉药物使用史、性虐待史、创伤史、高龄、慢性病和经济差距也会影响疼痛体验。文化因素进一步影响对疼痛的表达和反应。最终,将标准化测试、体格检查、心理因素(包括思维和情绪障碍及其对感知的影响)、继发获益、滥用史以及疼痛和治疗反应的情感维度相结合,体现了医学如何将艺术与科学融为一体。数字评分量表(NRS)是一种简单且广泛使用的工具,用于量化疼痛强度,患者从0(无疼痛)到10(可能的最严重疼痛)对自己的疼痛进行评分。尽管很受欢迎,但NRS仍然是一种粗略且通用的测量方法,缺乏一致性和客观验证。该量表在某些情况下很有用,例如评估心绞痛患者舌下含服硝酸甘油前后的疼痛,或评估老年患者的单纯骨折,疼痛评分为4可能与呼吸抑制相关。然而,NRS也有局限性。例如,患有肌筋膜疼痛或诊断不明确的患者,尽管生命体征稳定且有使用镇痛药的证据,但报告极度疼痛(如10/10),可能会引发对其寻求药物行为的担忧。在涉及“攻击性护送人员”或安静患者的情况下,临床医生应注意使用的语言,避免假设,并保持警惕。口服药物应在监督下给药,以防止“分享”或转移,因为“藏药”以备后用或贩卖很常见。有主导交流的护送人员在场时,需要仔细评估是否存在潜在的滥用或贩卖行为。视觉模拟量表的功能与NRS类似,但可能包含图像元素,以帮助那些与临床医生语言不通的患者。该量表由一条两端分别标有“无疼痛”和“可能的最严重疼痛”的线组成,患者在上面标记自己的疼痛程度。得分对应于从“无疼痛”到标记处的距离。VAS与NRS有相同的局限性。面部表情疼痛评分量表是为急性环境中可能无法言语的儿童设计的,也可适用于有沟通困难的成年人。(来源:面部表情疼痛评分量表历史,2016年)非语言疼痛量表在重症监护病房特别有用,可用于评估非语言成年人的疼痛,如插管但未完全镇静的患者。行为疼痛量表提供了一种观察方法,用于评估镇静或昏迷患者的疼痛。该工具评估面部表情、上肢运动以及对机械通气的依从性。有效使用需要相当多的经验,并在临床背景下进行解读,包括对生命体征的解读。例如,心动过速可能表明痛苦或缓解,这取决于患者使用的药物,如β受体阻滞剂或钙通道阻滞剂,这些药物在重症监护病房患者中常用,无论其通气状态如何。简短健康调查问卷36包含36个问题,评估多个健康领域,包括身体功能、角色限制、身体疼痛、总体健康、活力、社会功能、情感角色和心理健康。虽然它不仅仅是一个疼痛评估工具,但它可作为慢性疼痛患者生活质量的客观衡量标准。该工具可用于指导慢性治疗决策。对于其在不同人群中的效用,意见不一。常见的“在最痛的地方捏我的手”方法是最差的工具。麦吉尔疼痛问卷(MPQ)是一种自我报告工具,旨在评估疼痛的质量和强度。该问卷列出了78个描述词,分为感觉、情感和评价类别,让患者选择最能描述其疼痛体验的词语。MPQ提供了一种定量测量方法,有助于随时间跟踪疼痛并评估治疗效果。MPQ的价值在于区分情感-躯体描述词,如“痛苦的”、“可怕的”和“折磨人的”,与感觉描述词,如“尖锐的”、“钝痛的”、“搏动性的”或“持续性的”。

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