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英国生物银行认知测试的信度和效度。

Reliability and validity of the UK Biobank cognitive tests.

机构信息

Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, United Kingdom.

Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom.

出版信息

PLoS One. 2020 Apr 20;15(4):e0231627. doi: 10.1371/journal.pone.0231627. eCollection 2020.

Abstract

UK Biobank is a health resource with data from over 500,000 adults. The cognitive assessment in UK Biobank is brief and bespoke, and is administered without supervision on a touchscreen computer. Psychometric information on the UK Biobank cognitive tests are limited. Despite the non-standard nature of these tests and the limited psychometric information, the UK Biobank cognitive data have been used in numerous scientific publications. The present study examined the validity and short-term test-retest reliability of the UK Biobank cognitive tests. A sample of 160 participants (mean age = 62.59, SD = 10.24) was recruited who completed the UK Biobank cognitive assessment and a range of well-validated cognitive tests ('reference tests'). Fifty-two participants returned 4 weeks later to repeat the UK Biobank tests. Correlations were calculated between UK Biobank tests and reference tests. Two measures of general cognitive ability were created by entering scores on the UK Biobank cognitive tests, and scores on the reference tests, respectively, into separate principal component analyses and saving scores on the first principal component. Four-week test-retest correlations were calculated for UK Biobank tests. UK Biobank cognitive tests showed a range of correlations with their respective reference tests, i.e. those tests that are thought to assess the same underlying cognitive ability (mean Pearson r = 0.53, range = 0.22 to 0.83, p≤.005). The measure of general cognitive ability based on the UK Biobank cognitive tests correlated at r = 0.83 (p < .001) with a measure of general cognitive ability created using the reference tests. Four-week test-retest reliability of the UK Biobank tests were moderate-to-high (mean Pearson r = 0.55, range = 0.40 to 0.89, p≤.003). Despite the brief, non-standard nature of the UK Biobank cognitive tests, some tests showed substantial concurrent validity and test-retest reliability. These psychometric results provide currently-lacking information on the validity of the UK Biobank cognitive tests.

摘要

英国生物库是一个拥有超过 50 万成年人数据的健康资源。英国生物库的认知评估简短而独特,在触摸屏计算机上无需监督即可进行。英国生物库认知测试的心理测量信息有限。尽管这些测试具有非标准性质且心理测量信息有限,但英国生物库认知数据已在众多科学出版物中使用。本研究检查了英国生物库认知测试的有效性和短期重测信度。招募了 160 名参与者(平均年龄= 62.59,SD = 10.24),他们完成了英国生物库认知评估和一系列经过充分验证的认知测试(“参考测试”)。52 名参与者在 4 周后返回重复进行英国生物库测试。计算了英国生物库测试与参考测试之间的相关性。通过分别将英国生物库认知测试和参考测试的分数输入到单独的主成分分析中,并保存第一主成分的分数,创建了两种一般认知能力的衡量标准。计算了英国生物库测试的 4 周重测信度。英国生物库认知测试与各自的参考测试之间存在一系列相关性,即那些被认为评估相同潜在认知能力的测试(平均皮尔逊 r = 0.53,范围为 0.22 至 0.83,p≤.005)。基于英国生物库认知测试的一般认知能力衡量标准与使用参考测试创建的一般认知能力衡量标准相关 r = 0.83(p <.001)。英国生物库测试的 4 周重测信度为中等至高(平均皮尔逊 r = 0.55,范围为 0.40 至 0.89,p≤.003)。尽管英国生物库认知测试简短且具有非标准性质,但一些测试显示出相当大的同时有效性和重测信度。这些心理测量结果提供了目前关于英国生物库认知测试有效性的信息。

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