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一名年轻成年男性起源于三叉神经的非典型畸胎样/横纹肌样瘤:病例报告及文献复习

Atypical Teratoid/Rhabdoid Tumor Originated From the Trigeminal Nerve in a Young Male Adult: Case Report and Review of the Literature.

作者信息

Chen Fuxiang, Mei Wenzhong, Lu Wen, Zeng Tiefa, Kang Dezhi, Wu Xiyue, You Honghai

机构信息

Department of Neurosurgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.

Department of Disease Prevention and Healthcare, Fujian Provincial Hospital, Fuzhou, China.

出版信息

Front Neurol. 2020 Apr 21;11:265. doi: 10.3389/fneur.2020.00265. eCollection 2020.

Abstract

Atypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant central nervous system neoplasm predominantly found in children under the age of 3 years, and is extremely rare in adults. There is no specific clinical presentations or radiological features in reported cases of AT/RT. Diagnosis of brain AT/RT is mainly dependent on the classical pathological characteristics. We report a rare case of AT/RT arising from the trigeminal nerve and leading to progressively multiple cranial nerve palsies in a 25-year-old male patient. Microsurgical resection of the tumor has been performed and confirmed the diagnosis by postoperative pathology. To our knowledge, this is the second case of adult-onset AT/RT originating from the trigeminal nerve.

摘要

非典型畸胎样/横纹肌样瘤(AT/RT)是一种高度恶性的中枢神经系统肿瘤,主要见于3岁以下儿童,在成人中极为罕见。已报道的AT/RT病例没有特异性临床表现或影像学特征。脑AT/RT的诊断主要依赖于典型的病理特征。我们报告1例罕见的起源于三叉神经并导致1例25岁男性患者逐渐出现多发性颅神经麻痹的AT/RT。已对肿瘤进行了显微手术切除,并通过术后病理证实了诊断。据我们所知,这是第二例起源于三叉神经的成人发病的AT/RT。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1299/7186469/8fb128260989/fneur-11-00265-g0001.jpg

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