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新型冠状病毒肺炎与辅助生殖技术服务:对患者的影响及个体化临床处理建议。

COVID-19 and assisted reproductive technology services: repercussions for patients and proposal for individualized clinical management.

机构信息

Department of Neuroscience, Reproductive Science and Odontostomatology, University of Naples Federico II, Via Sergio Pansini 5, 80131, Naples, Italy.

ANDROFERT, Andrology and Human Reproduction Clinic, Av. Dr. Heitor Penteado, 1463, Campinas, SP, 13075-460, Brazil.

出版信息

Reprod Biol Endocrinol. 2020 May 13;18(1):45. doi: 10.1186/s12958-020-00605-z.

Abstract

The prolonged lockdown of health services providing high-complexity fertility treatments -as currently recommended by many reproductive medicine entities- is detrimental for society as a whole, and infertility patients in particular. Globally, approximately 0.3% of all infants born every year are conceived using assisted reproductive technology (ART) treatments. By contrast, the total number of COVID-19 deaths reported so far represents approximately 1.0% of the total deaths expected to occur worldwide over the first three months of the current year. It seems, therefore, that the number of infants expected to be conceived and born -but who will not be so due to the lockdown of infertility services- might be as significant as the total number of deaths attributed to the COVID-19 pandemic. We herein propose remedies that include a prognostic-stratification of more vulnerable infertility cases in order to plan a progressive restart of worldwide fertility treatments. At a time when preventing complications and limiting burdens for national health systems represent relevant issues, our viewpoint might help competent authorities and health care providers to identify patients who should be prioritized for the continuation of fertility care in a safe environment.

摘要

目前,许多生殖医学机构建议延长提供高复杂性生育治疗服务的封锁,这对整个社会,特别是不孕患者都有不利影响。在全球范围内,每年出生的所有婴儿中,约有 0.3%是通过辅助生殖技术(ART)治疗受孕的。相比之下,到目前为止报告的 COVID-19 死亡总数约占今年前三个月全球预期总死亡人数的 1.0%。因此,由于不孕服务的封锁而无法受孕和出生的婴儿数量可能与 COVID-19 大流行导致的总死亡人数一样多。在此,我们提出了一些补救措施,包括对更脆弱的不孕病例进行预后分层,以便为全球生育治疗的逐步重启做好计划。在预防并发症和为国家卫生系统减轻负担成为相关问题的情况下,我们的观点可能有助于主管当局和医疗保健提供者确定应优先在安全环境中继续生育护理的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c13b/7218830/b60fd1031390/12958_2020_605_Fig1_HTML.jpg

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