Neurology Department, KAT General Hospital of Attica, 2 Nikis Str., Kifisia, Attica, 14561, Athens, Greece.
J Neurol. 2020 Sep;267(9):2485-2489. doi: 10.1007/s00415-020-09939-5. Epub 2020 May 26.
Coronavirus disease 2019 (COVID-19) has become a pandemic disease globally. While it mostly presents with respiratory symptoms, it has already been found that it could manifest with a series of neurological symptoms as well, either at presentation or during the course of the disease. Symptoms vary from non-specific such as headache or dizziness to more specific such as convulsions and cerebrovascular disease (CVD). This study aims to give an overview of the neurological manifestations of COVID-19 and discuss the potential pathogenetic mechanisms of central nervous system (CNS) involvement. Clinicians and especially internists, neurologists, and infectious disease specialists should be aware of these symptoms and able to recognize them early. Prompt diagnosis and immediate management of the neurological manifestations of the novel coronavirus will not only improve the prognosis of COVID-19 patients but will also prevent the dissemination of the disease due to misdiagnosed cases.
新型冠状病毒肺炎(COVID-19)已在全球范围内成为一种大流行疾病。虽然它主要表现为呼吸道症状,但已经发现它也可能在发病时或疾病过程中出现一系列神经系统症状。症状从非特异性如头痛或头晕到更特异性如抽搐和脑血管疾病(CVD)不等。本研究旨在概述 COVID-19 的神经系统表现,并讨论中枢神经系统(CNS)受累的潜在发病机制。临床医生,特别是内科医生、神经科医生和传染病专家,应该了解这些症状,并能够及早识别它们。及时诊断和治疗新型冠状病毒的神经系统表现,不仅可以改善 COVID-19 患者的预后,还可以防止因误诊而导致疾病的传播。