使用更新的 EWGSOP2 定义诊断肌少症的影响：临床视角。
Impact of using the updated EWGSOP2 definition in diagnosing sarcopenia: A clinical perspective.
机构信息
Department of Human Movement Sciences, @AgeAmsterdam, Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Amsterdam, the Netherlands.
Geriatric Research Unit, Geriatric Department, Bispebjerg and Frederiksberg University Hospital, Denmark; GENUD Toledo Research Group, Universidad de Castilla-La Mancha, Toledo, Spain.
出版信息
Arch Gerontol Geriatr. 2020 Sep-Oct;90:104125. doi: 10.1016/j.archger.2020.104125. Epub 2020 May 23.
BACKGROUND AND PURPOSE
The revised European Working Group on Sarcopenia in Older People (EWGSOP2, version 2019) definition of sarcopenia differs with respect to the EWGSOP (version 2010) definition in applied criteria and their cut-off values. We aimed to investigate the impact of the new definition on sarcopenia prevalence in various populations of older adults.
METHODS
Eight cohorts, including community-dwelling older adults, geriatric outpatients and patients admitted to acute and subacute inpatient wards were assessed on sarcopenia prevalence.
RESULTS
A total of 2256 participants (56.4 % female) were included with a median age of the cohorts of 71.7-83.3 years. In males, sarcopenia prevalence was 31.9 % according to EWGSOP compared to 12.0 % according to EWGSOP2. In females, sarcopenia prevalence was 4.9 % and 6.1 % according to EWGSOP and EWGSOP2 respectively. Lower cut-off points for handgrip strength (27 kg versus 30 kg (males) and 16 kg versus 20 kg (females) for EWGSOP and EWGSOP2 respectively) resulted in the lower sarcopenia prevalence in males.
CONCLUSIONS
According to the EWGSOP2 definition, the prevalence of sarcopenia in males is significantly lower compared to the EWGSOP definition, whereas the prevalence among women is slightly higher. The lower cut-off points for handgrip strength result in fewer adults being diagnosed with sarcopenia.
背景与目的
修订后的欧洲老年人肌少症工作组（EWGSOP2，2019 年版）定义与 EWGSOP（2010 年版）定义在应用标准和截断值方面有所不同。我们旨在研究新定义对不同老年人群体肌少症患病率的影响。
方法
对 8 个队列（包括社区居住的老年人、老年门诊患者和急性和亚急性住院病房的患者）进行肌少症患病率评估。
结果
共纳入 2256 名参与者（56.4%为女性），年龄中位数为 71.7-83.3 岁。男性中，根据 EWGSOP 定义的肌少症患病率为 31.9%，而根据 EWGSOP2 定义的患病率为 12.0%。女性中，根据 EWGSOP 和 EWGSOP2 定义的肌少症患病率分别为 4.9%和 6.1%。握力较低的截断点（男性分别为 27 公斤和 30 公斤（EWGSOP 和 EWGSOP2），女性分别为 16 公斤和 20 公斤（EWGSOP 和 EWGSOP2））导致男性肌少症的患病率较低。
结论
根据 EWGSOP2 定义，男性肌少症的患病率明显低于 EWGSOP 定义，而女性的患病率略高。握力较低的截断点导致较少的成年人被诊断为肌少症。
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