VRmol：一个整合的基于网络的虚拟现实系统，用于探索大分子结构。
VRmol: an integrative web-based virtual reality system to explore macromolecular structure.
机构信息
MOE Key Laboratory of Bioinformatics, School of Life Sciences, Beijing 100084, China.
Beijing Advanced Innovation Center for Structural Biology, Beijing Frotier Research Center for Biological Structures, Beijing 100084, China.
出版信息
Bioinformatics. 2021 May 17;37(7):1029-1031. doi: 10.1093/bioinformatics/btaa696.
SUMMARY
Structural visualization and analysis are fundamental to explore macromolecular functions. Here, we present a novel integrative web-based virtual reality (VR) system-VRmol, to visualize and study molecular structures in an immersive virtual environment. Importantly, it is integrated with multiple online databases and is able to couple structure studies with associated genomic variations and drug information in a visual interface by cloud-based drug docking. VRmol thus can serve as an integrative platform to aid structure-based translational research and drug design.
AVAILABILITY AND IMPLEMENTATION
VRmol is freely available (https://VRmol.net), with detailed manual and tutorial (https://VRmol.net/docs). The code of VRmol is available as open source under the MIT license at http://github.com/kuixu/VRmol.
SUPPLEMENTARY INFORMATION
Supplementary data are available at Bioinformatics online.
摘要
结构可视化和分析是探索大分子功能的基础。在这里，我们提出了一个新的基于网络的集成虚拟现实（VR）系统-VRmol，可在沉浸式虚拟环境中可视化和研究分子结构。重要的是，它与多个在线数据库集成，并能够通过基于云的药物对接在可视化界面中将结构研究与相关的基因组变异和药物信息联系起来。因此，VRmol 可以作为一个整合平台，辅助基于结构的转化研究和药物设计。
可用性和实现
VRmol 可免费使用（https://VRmol.net），并提供详细的手册和教程（https://VRmol.net/docs）。VRmol 的代码作为开源代码，根据麻省理工学院的许可协议在 http://github.com/kuixu/VRmol 上提供。
补充信息
补充数据可在生物信息学在线获得。
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