微生物组在宿主进化中的作用。
The role of the microbiome in host evolution.
机构信息
Department of Ecology, Evolution, and Behavior, The Hebrew University of Jerusalem, Giv'at Ram, Jerusalem, Israel.
Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.
出版信息
Philos Trans R Soc Lond B Biol Sci. 2020 Sep 28;375(1808):20190588. doi: 10.1098/rstb.2019.0588. Epub 2020 Aug 10.
In the last decade, we have witnessed a major paradigm shift in the life sciences: the recognition that the microbiome, i.e. the set of microorganisms associated with healthy animals (including humans) and plants, plays a crucial role in the sustained health and fitness of its host. Enabled by rapid advances in sequencing technologies and analytical methods, substantial advances have been achieved in both identifying the microbial taxa and understanding the relationship between microbiome composition and host phenotype. These breakthroughs are leading to novel strategies for improved human and animal health, enhanced crop yield and nutritional quality, and the control of various pests and disease agents. This article is part of the theme issue 'The role of the microbiome in host evolution'.
在过去的十年中，我们见证了生命科学领域的重大范式转变：即认识到微生物组（即与健康动物（包括人类）和植物相关的微生物集合）在维持其宿主的健康和适应性方面起着至关重要的作用。得益于测序技术和分析方法的快速进步，在鉴定微生物类群和理解微生物组组成与宿主表型之间的关系方面都取得了重大进展。这些突破正在为改善人类和动物健康、提高作物产量和营养价值以及控制各种害虫和疾病媒介提供新的策略。本文是主题为“微生物组在宿主进化中的作用”的特刊的一部分。
Zotero 插件