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智能手机应用程序中基于跨诊断认知行为干预治疗进食障碍心理病理的随机对照试验

Efficacy of a transdiagnostic cognitive-behavioral intervention for eating disorder psychopathology delivered through a smartphone app: a randomized controlled trial.

机构信息

School of Psychology, Deakin University, 1 Gheringhap Street, Geelong, VIC 3220, Australia.

Federation University, School of Science, Engineering & Information Technology, Melbourne, Australia.

出版信息

Psychol Med. 2022 Jul;52(9):1679-1690. doi: 10.1017/S0033291720003426. Epub 2020 Sep 25.

Abstract

BACKGROUND

Although effective treatments exist for diagnostic and subthreshold-level eating disorders (EDs), a significant proportion of affected individuals do not receive help. Interventions translated for delivery through smartphone apps may be one solution towards reducing this treatment gap. However, evidence for the efficacy of smartphones apps for EDs is lacking. We developed a smartphone app based on the principles and techniques of transdiagnostic cognitive-behavioral therapy for EDs and evaluated it through a pre-registered randomized controlled trial.

METHODS

Symptomatic individuals (those who reported the presence of binge eating) were randomly assigned to the app ( = 197) or waiting list ( = 195). Of the total sample, 42 and 31% exhibited diagnostic-level bulimia nervosa and binge-eating disorder symptoms, respectively. Assessments took place at baseline, 4 weeks, and 8 weeks post-randomization. Analyses were intention-to-treat. The primary outcome was global levels of ED psychopathology. Secondary outcomes were other ED symptoms, impairment, and distress.

RESULTS

Intervention participants reported greater reductions in global ED psychopathology than the control group at post-test ( = -0.80). Significant effects were also observed for secondary outcomes ('s = -0.30 to -0.74), except compensatory behavior frequency. Symptom levels remained stable at follow-up. Participants were largely satisfied with the app, although the overall post-test attrition rate was 35%.

CONCLUSION

Findings highlight the potential for this app to serve as a cost-effective and easily accessible intervention for those who cannot receive standard treatment. The capacity for apps to be flexibly integrated within current models of mental health care delivery may prove vital for addressing the unmet needs of people with EDs.

摘要

背景

尽管存在有效的诊断和阈下饮食障碍(ED)治疗方法,但仍有相当一部分患者未得到治疗。通过智能手机应用程序进行干预可能是减少这种治疗差距的一种解决方案。然而,目前缺乏智能手机应用程序治疗 ED 的疗效证据。我们基于 ED 的跨诊断认知行为治疗的原则和技术开发了一款智能手机应用程序,并通过预先注册的随机对照试验对其进行了评估。

方法

症状患者(即报告存在暴食行为的患者)被随机分配到应用程序组(n=197)或等待名单组(n=195)。在总样本中,分别有 42%和 31%的患者表现出诊断水平的神经性贪食症和暴食障碍症状。评估在基线、4 周和 8 周后进行。分析采用意向治疗。主要结局是 ED 心理病理学的总体水平。次要结局是其他 ED 症状、损害和痛苦。

结果

与对照组相比,干预组患者在测试后报告的 ED 心理病理总体水平降低更大( = -0.80)。除了代偿行为频率外,其他次要结局也观察到显著效果('s = -0.30 至 -0.74)。在随访时,症状水平保持稳定。尽管整体测试后退出率为 35%,但参与者对应用程序的满意度较高。

结论

研究结果强调了该应用程序作为那些无法接受标准治疗的患者的一种经济有效的、易于获取的干预手段的潜力。应用程序能够灵活地整合到当前的心理健康护理提供模式中,可能对满足 ED 患者的未满足需求至关重要。

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