由甲氧苄啶-磺胺甲恶唑不良反应引发的史蒂文斯-约翰逊综合征

Stevens Johnson Syndrome Initiated by an Adverse Reaction to Trimethoprim-Sulfamethoxazole.

作者信息

Buganu Adelina, Atta Massud, Solomon Matthew, Banerjee Paul R, Ganti Latha

机构信息

Emergency Medicine, Coliseum Medical Centers, Macon, USA.

Emergency Medicine, Brown University, Providence, USA.

出版信息

Cureus. 2020 Aug 25;12(8):e10023. doi: 10.7759/cureus.10023.

DOI:10.7759/cureus.10023

PMID:32983718

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7515742/

Abstract

The authors present a case of a 54-year-old male who presented to the ED with Stevens Johnson syndrome (SJS) beginning on his upper lips, then spreading to his glans penis, airway, and buttocks. After using trimethoprim-sulfamethoxazole (TMP-SMX) to treat a pilonidal cyst diagnosed seven days prior to presentation, the patient began to have desquamating lesions on his upper and lower lips. Subsequently, he noticed desquamation on the glans penis and then between his buttocks. Before being referred to dermatology, he was treated with a high dosage of corticosteroids.

摘要

作者报告了一例54岁男性病例，该患者因史蒂文斯-约翰逊综合征（SJS）就诊于急诊科，最初病变始于上唇，随后蔓延至阴茎龟头、气道和臀部。在使用甲氧苄啶-磺胺甲恶唑（TMP-SMX）治疗就诊前七天诊断出的藏毛窦囊肿后，患者开始在上、下唇出现脱皮性病变。随后，他注意到阴茎龟头以及臀部之间出现脱皮。在转诊至皮肤科之前，他接受了高剂量皮质类固醇治疗。