Zoonotic Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Department of Environmental Health Engineering, Faculty of Health, Ilam University of Medical Sciences, Ilam, Iran.
Environ Sci Pollut Res Int. 2021 Jan;28(1):1-15. doi: 10.1007/s11356-020-11060-z. Epub 2020 Oct 2.
Recently, an outbreak of a novel human coronavirus which is referred to as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (COVID-19) by the World Health Organization (WHO) was identified in Wuhan, China. To help combat the pandemic, a systematic review (SR) was performed to collect all available studies concerning inactivation methods, environmental survival, and control and prevention strategies. A comprehensive literature survey yielded 42 eligible studies which included in the SR. The results confirmed that the WHO recommended two alcohol-based hand rub formulations (ethanol 70-95% and 2-propanol 70-100%) had an efficient virucidal activity in less than 60 s by more and equal 4 log (≥ 99.99) approximately and could be used for disinfection in public health and health-care facilities. The findings indicated that SARS-CoV-1 and SARS-CoV-2 can survive under different environmental conditions between 4 and 72 h approximately. The results also demonstrate that temperature and relative humidity are important factors in the survival of SARS-CoV-2. The main strategies recommended by the WHO to avoid contracting SARS-CoV-2 are hand washing several times in the day and maintaining social distancing with others. It is important to note that the more studies require addressing, the more possible airborne transmission due to the survival of SARS-CoV-2 in aerosols for 3 h approximately. We hope that the results of the present SR can help researchers, health decision-makers, policy-makers, and people for understanding and taking the proper behavior to control and prevent further spread of SARS-CoV-2.
最近,世界卫生组织(WHO)将一种新型人类冠状病毒命名为严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)(COVID-19),在中国武汉爆发。为了帮助应对这一疫情,我们进行了一项系统评价(SR),以收集所有关于灭活方法、环境存活以及控制和预防策略的可用研究。全面的文献调查产生了 42 项符合纳入标准的研究,这些研究都包含在本次 SR 中。结果证实,WHO 推荐的两种酒精基手部消毒剂配方(乙醇 70-95%和 2-丙醇 70-100%)在不到 60 秒的时间内即可有效杀灭病毒,大约能减少 4 个对数(≥99.99%),可用于公共卫生和医疗机构的消毒。研究结果表明,SARS-CoV-1 和 SARS-CoV-2 在 4 至 72 小时左右的不同环境条件下均可存活。结果还表明,温度和相对湿度是 SARS-CoV-2 存活的重要因素。WHO 推荐的避免感染 SARS-CoV-2 的主要策略是每天多次洗手并与他人保持社交距离。需要注意的是,由于 SARS-CoV-2 在气溶胶中大约可存活 3 小时,因此需要进一步开展更多研究来确定其是否存在空气传播的可能。我们希望本次 SR 的结果能够帮助研究人员、卫生决策者、政策制定者和民众了解并采取适当的行为来控制和预防 SARS-CoV-2 的进一步传播。