FlyRNAi.org——果蝇 RNAi 筛选中心和转基因 RNAi 项目数据库：2021 年更新。
FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2021 update.
机构信息
Department of Genetics, Blavatnik Institute, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.
Drosophila RNAi Screening Center, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA.
出版信息
Nucleic Acids Res. 2021 Jan 8;49(D1):D908-D915. doi: 10.1093/nar/gkaa936.
The FlyRNAi database at the Drosophila RNAi Screening Center and Transgenic RNAi Project (DRSC/TRiP) provides a suite of online resources that facilitate functional genomics studies with a special emphasis on Drosophila melanogaster. Currently, the database provides: gene-centric resources that facilitate ortholog mapping and mining of information about orthologs in common genetic model species; reagent-centric resources that help researchers identify RNAi and CRISPR sgRNA reagents or designs; and data-centric resources that facilitate visualization and mining of transcriptomics data, protein modification data, protein interactions, and more. Here, we discuss updated and new features that help biological and biomedical researchers efficiently identify, visualize, analyze, and integrate information and data for Drosophila and other species. Together, these resources facilitate multiple steps in functional genomics workflows, from building gene and reagent lists to management, analysis, and integration of data.
果蝇 RNAi 筛选中心和转(transgenic) RNAi 项目 (DRSC/TRiP) 的 FlyRNAi 数据库提供了一系列在线资源，特别强调黑腹果蝇的功能基因组学研究。目前，该数据库提供了：以基因为中心的资源，方便进行同源基因映射，并挖掘常见遗传模式物种中同源基因的信息；以试剂为中心的资源，帮助研究人员鉴定 RNAi 和 CRISPR sgRNA 试剂或设计；以及以数据为中心的资源，方便进行转录组学数据、蛋白质修饰数据、蛋白质相互作用等的可视化和挖掘。在这里，我们将讨论更新和新的功能，帮助生物和生物医学研究人员高效地识别、可视化、分析和整合果蝇和其他物种的信息和数据。这些资源共同促进了功能基因组学工作流程的多个步骤，从构建基因和试剂列表到数据的管理、分析和整合。
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