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维生素D在小动物骨骼代谢中的作用。

The Role of Vitamin D in Small Animal Bone Metabolism.

作者信息

Zafalon Rafael Vessecchi Amorim, Ruberti Bruna, Rentas Mariana Fragoso, Amaral Andressa Rodrigues, Vendramini Thiago Henrique Annibale, Chacar Fernanda Chicharo, Kogika Marcia Mery, Brunetto Marcio Antonio

机构信息

Pet Nutrology Research Center, Nutrition and Production Department, School of Veterinary Medicine and Animal Science, University of São Paulo, Jardim Elite, Pirassununga 13635-900, Brazil.

Small Animal Internal Medicine Service, Veterinary Teaching Hospital, School of Veterinary Medicine and Animal Science, University of São Paulo, Cidade Universitária, São Paulo 05508-270, Brazil.

出版信息

Metabolites. 2020 Dec 3;10(12):496. doi: 10.3390/metabo10120496.

Abstract

Dogs and cats have differences in vitamin D metabolism compared to other mammalian species, as they are unable to perform vitamin D cutaneous synthesis through sun exposure. Therefore, they are dependent on the dietary intake of this nutrient. The classic functions of vitamin D are to stimulate intestinal calcium and phosphate absorption, renal calcium and phosphate reabsorption and regulate bone mineral metabolism. Thus, it is an important nutrient for calcium and phosphorus homeostasis. This review highlights the evidence of the direct and indirect actions of vitamin D on bone mineral metabolism, the consequences of nutritional imbalances of this nutrient in small animals, as well as differences in vitamin D metabolism between different size dogs.

摘要

与其他哺乳动物相比,狗和猫在维生素D代谢方面存在差异,因为它们无法通过晒太阳进行维生素D的皮肤合成。因此,它们依赖于这种营养素的饮食摄入。维生素D的经典功能是刺激肠道对钙和磷的吸收、肾脏对钙和磷的重吸收以及调节骨矿物质代谢。因此,它是钙和磷稳态的重要营养素。这篇综述强调了维生素D对骨矿物质代谢的直接和间接作用的证据、这种营养素营养失衡在小动物中的后果,以及不同体型犬之间维生素D代谢的差异。

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