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维生素C与心血管疾病:最新进展

Vitamin C and Cardiovascular Disease: An Update.

作者信息

Morelli Marco B, Gambardella Jessica, Castellanos Vanessa, Trimarco Valentina, Santulli Gaetano

机构信息

Division of Cardiology, Department of Medicine, Institute of Aging Research, Wilf Family Cardiovascular Research Institute, Albert Einstein College of Medicine, Montefiore University Hospital, New York, NY 10461, USA.

Department of Molecular Pharmacology, Fleischer Institute for Diabetes and Metabolism (FIDAM), Einstein-Sinai Diabetes Research Center (ES-DRC), Albert Einstein College of Medicine, New York, NY 10461, USA.

出版信息

Antioxidants (Basel). 2020 Dec 3;9(12):1227. doi: 10.3390/antiox9121227.

Abstract

The potential beneficial effects of the antioxidant properties of vitamin C have been investigated in a number of pathological conditions. In this review, we assess both clinical and preclinical studies evaluating the role of vitamin C in cardiac and vascular disorders, including coronary heart disease, heart failure, hypertension, and cerebrovascular diseases. Pitfalls and controversies in investigations on vitamin C and cardiovascular disorders are also discussed.

摘要

维生素C抗氧化特性的潜在有益作用已在多种病理状况下进行了研究。在本综述中,我们评估了临床和临床前研究,这些研究评估了维生素C在心脏和血管疾病中的作用,包括冠心病、心力衰竭、高血压和脑血管疾病。还讨论了维生素C与心血管疾病研究中的陷阱和争议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cec4/7761826/6b40459ebf5f/antioxidants-09-01227-g001.jpg

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