氧化亚氮所致中毒性脑白质病。
Nitrous oxide-induced toxic leukoencephalopathy.
机构信息
Anaesthesia, Leicester Royal Infirmary, Leicester, UK
Radiology, Leicester Royal Infirmary, Leicester, UK.
出版信息
BMJ Case Rep. 2020 Dec 10;13(12):e238315. doi: 10.1136/bcr-2020-238315.
Abstract
Toxic leukoencephalopathy (TL) is characterised by an insult to the myelin of the cerebral white manner which can be attributed to a number of offending agents, including drugs of abuse. We report a case of a fit and well young man presenting to hospital with an altered mental state. It was subsequently determined that the patient inhaled a significant volume of nitrous oxide recreationally. Nitrous oxide is easily accessible and the second most consumed drug among young adolescents (16-24 years old). Following extensive investigations and brain imaging, the patient was subsequently diagnosed with TL. After a prolonged hospital admission, he went on to make a complete neurological recovery.
摘要
中毒性脑白质病（TL）的特征是大脑白质的髓鞘受到损伤，这可归因于许多致病因子，包括滥用药物。我们报告了一例身体状况良好的年轻男性，因精神状态改变而到医院就诊。随后确定该患者因娱乐性吸入了大量一氧化二氮。一氧化二氮很容易获得，是青少年（16-24 岁）中第二大消费药物。经过广泛的调查和脑部成像，该患者随后被诊断为 TL。经过长时间的住院治疗，他完全恢复了神经功能。
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