Westmead Clinical School, The University of Sydney, Sydney, NSW, Australia; Centre for Kidney Research, The Children's Hospital at Westmead, Westmead, NSW, Australia; Nutrition and Dietetics Department, St George Hospital, Kogarah, NSW, Australia.
Menzies Health Institute, Griffith University, Brisbane, QLD, Australia; Allied Health Services, Metro North Hospital and Health Service, Brisbane, QLD, Australia.
Am J Kidney Dis. 2021 Jul;78(1):85-95.e1. doi: 10.1053/j.ajkd.2020.11.015. Epub 2021 Jan 7.
RATIONALE & OBJECTIVE: An important component of hemodialysis management involves delivery of complex dietary recommendations. The aim of this study was to determine the feasibility of a mobile phone text-message intervention to improve dietary behavior in people undergoing hemodialysis.
Six-month randomized feasibility study.
SETTING & PARTICIPANTS: Patients receiving maintenance hemodialysis across 2 health districts in Sydney, Australia.
Participants randomized to the intervention received 3 text messages per week in addition to standard dietary care for 6 months. The usual care group received standard dietary care.
The primary outcomes were feasibility measured using recruitment and retention rates, acceptability of the intervention, and adherence to dietary recommendations. Secondary exploratory outcomes included information on certain clinical parameters related to dietary management of patients receiving maintenance hemodialysis.
130 people were recruited; 48% of eligible patients (130 of 272) consented to participate, and 88% (115 of 130) completed the study. Semistructured interviews evaluating acceptability identified 5 themes: clear and comprehensive, engaging with consistent and relevant content, maintaining attention with timely reminders, sustaining interest through ongoing care, and generic messages inadequate to prompt dietary change. There was no difference in adherence to dietary recommendations across treatment groups (odds ratio, 1.21 [95% CI, 0.55-2.72]; P = 0.6). Secondary exploratory analyses suggested reductions in dietary intake of single nutrients (potassium, phosphorus, sodium, protein), interdialytic weight gain, and phosphate binder use among intervention participants compared with participants assigned to standard care.
Our feasibility study was of short duration. Adherence was based on self-reported data. Generalizability to populations receiving maintenance hemodialysis outside of an urban, Australian setting is unknown.
A simple mobile phone text-messaging intervention was feasible and acceptable to patients. Further investigation of the impact on patient-reported and clinical outcomes is warranted.
Funding for the study was provided by a Sydney Medical School Foundation Grant and the Centre for Transplant and Renal Research at Westmead Hospital.
Registered at Australian New Zealand Clinical Trials Registry with study number ACTRN12617001084370.
血液透析管理的一个重要组成部分涉及提供复杂的饮食建议。本研究的目的是确定通过手机短信干预来改善血液透析患者饮食行为的可行性。
为期 6 个月的随机可行性研究。
澳大利亚悉尼 2 个卫生区接受维持性血液透析的患者。
除了标准饮食护理外,干预组每周还接受 3 条短信,共 6 个月。常规护理组接受标准饮食护理。
采用招募和保留率、干预措施的可接受性和对饮食建议的依从性来衡量主要结局。次要探索性结局包括与接受维持性血液透析患者的饮食管理相关的某些临床参数的信息。
共招募了 130 人;272 名符合条件的患者中,48%(130 名)同意参与,88%(130 名)完成了研究。评估可接受性的半结构化访谈确定了 5 个主题:清晰全面、用一致和相关的内容吸引、用及时的提醒保持注意力、通过持续的护理维持兴趣、通用消息不足以促使饮食改变。治疗组之间对饮食建议的依从性没有差异(比值比,1.21 [95%置信区间,0.55-2.72];P=0.6)。次要探索性分析表明,与接受标准护理的患者相比,干预组患者的单一营养素(钾、磷、钠、蛋白质)、透析间体重增加和磷酸盐结合剂使用减少。
我们的可行性研究持续时间较短。依从性基于自我报告的数据。在城市以外的澳大利亚环境中接受维持性血液透析的人群是否适用尚不清楚。
简单的手机短信干预对患者是可行且可接受的。需要进一步研究该干预对患者报告和临床结局的影响。
该研究由悉尼医学院基金会资助和韦斯特米德医院移植和肾脏研究中心提供。
在澳大利亚和新西兰临床试验注册中心注册,研究编号为 ACTRN12617001084370。