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Tackling immunosenescence to improve COVID-19 outcomes and vaccine response in older adults.

作者信息

Cox Lynne S, Bellantuono Ilaria, Lord Janet M, Sapey Elizabeth, Mannick Joan B, Partridge Linda, Gordon Adam L, Steves Claire J, Witham Miles D

机构信息

Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.

Healthy Lifespan Institute, Department of Oncology and Metabolism, The University of Sheffield, Sheffield, UK.

出版信息

Lancet Healthy Longev. 2020 Nov;1(2):e55-e57. doi: 10.1016/S2666-7568(20)30011-8. Epub 2020 Nov 9.

Abstract
摘要

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本文引用的文献

1
In-Hospital Use of Statins Is Associated with a Reduced Risk of Mortality among Individuals with COVID-19.
Cell Metab. 2020 Aug 4;32(2):176-187.e4. doi: 10.1016/j.cmet.2020.06.015. Epub 2020 Jun 24.
2
The quest to slow ageing through drug discovery.
Nat Rev Drug Discov. 2020 Aug;19(8):513-532. doi: 10.1038/s41573-020-0067-7. Epub 2020 May 28.
3
Simvastatin Improves Neutrophil Function and Clinical Outcomes in Pneumonia. A Pilot Randomized Controlled Clinical Trial.
Am J Respir Crit Care Med. 2019 Nov 15;200(10):1282-1293. doi: 10.1164/rccm.201812-2328OC.
4
Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study.
EBioMedicine. 2019 Feb;40:554-563. doi: 10.1016/j.ebiom.2018.12.052. Epub 2019 Jan 5.
5
mTORC Inhibitors as Broad-Spectrum Therapeutics for Age-Related Diseases.
Int J Mol Sci. 2018 Aug 8;19(8):2325. doi: 10.3390/ijms19082325.
6
TORC1 inhibition enhances immune function and reduces infections in the elderly.
Sci Transl Med. 2018 Jul 11;10(449). doi: 10.1126/scitranslmed.aaq1564.
7
Find drugs that delay many diseases of old age.
Nature. 2018 Feb 15;554(7692):293-295. doi: 10.1038/d41586-018-01668-0.
8
The effect of ageing of the immune system on vaccination responses.
Hum Vaccin Immunother. 2013 Jun;9(6):1364-7. doi: 10.4161/hv.24696. Epub 2013 Apr 12.

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