Faculty of Agricultural Sciences and Technologies, Nigde Omer Halisdemir University, 51000 Nigde, Turkey.
Department of Pharmaceutical Sciences, Section of Food Sciences and Nutrition, University of Perugia, Via S. Costanzo 1, 06126 Perugia, Italy.
Mar Drugs. 2021 Jan 29;19(2):71. doi: 10.3390/md19020071.
In fish processing, a great amount of side streams, including skin, bones, heads and viscera, is wasted or downgraded as feed on a daily basis. These side streams are rich sources of bioactive nitrogenous compounds and protein, which can be converted into peptides through enzymatic hydrolysis as well as bacterial fermentation. Peptides are short or long chains of amino acids differing in structure and molecular weight. They can be considered as biologically active as they can contribute to physiological functions in organisms with applications in the food and pharmaceutical industries. In the food industry, such bioactive peptides can be used as preservatives or antioxidants to prevent food spoilage. Furthermore, peptides contain several functional qualities that can be exploited as tools in modifying food ingredient solubility, water-holding and fat-binding capacity and gel formation. In the pharmaceutical industry, peptides can be used as antioxidants, but also as antihypertensive, anticoagulant and immunomodulatory compounds, amongst other functions. On the basis of their properties, peptides can thus be used in the development of functional foods and nutraceuticals. This review focuses on the bioactive peptides derived from seafood side streams and discusses their technological properties, biological activities and applications.
在鱼类加工过程中,大量的副产物,包括皮、骨、头和内脏,每天都被浪费或降级为饲料。这些副产物是生物活性含氮化合物和蛋白质的丰富来源,可以通过酶解和细菌发酵转化为肽。肽是结构和分子量不同的氨基酸短链或长链。它们可以被认为具有生物活性,因为它们可以为生物体的生理功能做出贡献,在食品和制药行业有应用。在食品工业中,这种生物活性肽可以用作防腐剂或抗氧化剂,以防止食品变质。此外,肽含有几种功能特性,可以用作工具来改变食品成分的溶解度、持水能力、脂肪结合能力和凝胶形成能力。在制药工业中,肽可用作抗氧化剂,也可用作抗高血压、抗凝血和免疫调节剂等化合物。基于它们的特性,肽可用于开发功能性食品和营养保健品。本文综述了从海鲜副产物中提取的生物活性肽,讨论了它们的技术特性、生物活性和应用。