Virginia Commonwealth University.
Child Dev. 2021 Mar;92(2):746-759. doi: 10.1111/cdev.13441. Epub 2020 Aug 9.
Childhood adversity is linked to shortened telomere length (TL), but behavioral indicators of telomere attrition remain unclear. This study examined the association between adverse childhood experiences (ACEs) and child TL, and if ACEs were indirectly associated with TL through children's self-regulatory abilities (i.e., effortful control and self-control). Hypotheses were tested using national data from teachers, parents, and their children (N = 2,527; M = 9.35, SD = .36 years). More ACEs were uniquely associated with short TL, and low self-control mediated the association between more ACEs and short TL. While longitudinal studies are needed to strengthen claims of causation, this study identifies a pathway from ACEs to TL that should be explored further.
童年逆境与端粒缩短有关,但端粒损耗的行为指标仍不清楚。本研究探讨了不良童年经历(ACEs)与儿童端粒的关系,以及 ACEs 是否通过儿童的自我调节能力(即努力控制和自我控制)间接地与 TL 相关。假设使用来自教师、家长及其子女的全国性数据进行了检验(N=2527;M=9.35,SD=.36 岁)。更多的 ACEs 与短端粒呈独特相关,低自我控制中介了 ACEs 与短端粒之间的关系。虽然需要进行纵向研究来加强因果关系的说法,但本研究确定了 ACEs 到 TL 的一个途径,应进一步探索。