Department of Clinical Science, Neurosciences, Umeå University, Umeå, Sweden.
Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Neurosurgery. 2021 Jun 15;89(1):122-128. doi: 10.1093/neuros/nyab094.
Gait and balance impairment are typical symptoms of idiopathic normal pressure hydrocephalus (INPH), implicating that falls may afflict these patients.
To investigate falls, related injuries, and associated psychological features, before and after shunt surgery for INPH and compared to the general population.
The study included 176 patients shunted for INPH and 368 age- and sex-matched controls. Falls, fear of falling (FOF), fall-related injuries (mild-severe), confidence in avoiding falls (Swedish Falls Efficacy Scale (FES(S)), quality of life (QoL; EuroQoL 5-dimension 5 level instrument), and symptoms of depression (Geriatric Depression Scale 15) were investigated. Pre- and postoperative observational times were 12 mo before surgery and 21 mo after (mean). Recurrent fallers fell ≥2 times.
More INPH patients than controls were recurrent fallers (67% vs 11%; P < .001). They feared falling more often (FOF, mean ± standard deviation: 3.3 ± 1.1 vs 1.6 ± 0.9; P < .001) and had lower confidence in avoiding falls (FES(S) 78 ± 40 vs 126 ± 14; P < .001). After surgery, INPH patients improved in all parameters but they did not reach the levels of the controls. Among fallers there was no difference between patients and controls in the severity of injuries suffered. Low QoL and symptoms of depression were more common among recurrent fallers than one-time or nonfallers in both shunted patients and controls (P ≤ .001).
Falls, FOF, and low confidence in avoiding falls are considerable problems in INPH that may be reduced by shunt surgery. We suggest that remaining risk of falling and preventative measures are routinely considered in postoperative follow-ups and rehabilitation planning.
步态和平衡障碍是特发性正常压力脑积水(INPH)的典型症状,这意味着这些患者可能会摔倒。
研究 INPH 患者分流术前和术后的跌倒、相关损伤和相关心理特征,并与普通人群进行比较。
本研究纳入了 176 例 INPH 分流患者和 368 例年龄和性别匹配的对照者。调查了跌倒、跌倒恐惧(FOF)、跌倒相关损伤(轻度-重度)、避免跌倒的信心(瑞典跌倒效能量表(FES(S))、生活质量(EuroQoL 五维五分制工具)和抑郁症状(老年抑郁量表 15)。术前和术后观察时间分别为手术前 12 个月和手术后 21 个月(平均值)。复发性跌倒者跌倒≥2 次。
与对照组相比,更多的 INPH 患者是复发性跌倒者(67% vs 11%;P<0.001)。他们更经常害怕跌倒(FOF,平均值±标准差:3.3±1.1 与 1.6±0.9;P<0.001),避免跌倒的信心较低(FES(S)78±40 与 126±14;P<0.001)。手术后,INPH 患者在所有参数上均有所改善,但仍未达到对照组的水平。在跌倒者中,无论是在患者还是在对照组中,受伤严重程度在患者和对照组之间均无差异。在接受分流术的患者和对照组中,复发性跌倒者的生活质量较低和抑郁症状较常见,而非单次或非跌倒者(P≤0.001)。
跌倒、跌倒恐惧和避免跌倒的信心不足是 INPH 的严重问题,分流手术可能会降低这些问题的发生率。我们建议,在术后随访和康复计划中,应常规考虑剩余的跌倒风险和预防措施。