Bai Wei, Cai Hong, Liu Shou, Liu Huanzhong, Qi Han, Chen Xu, Liu Rui, Cheung Teris, Su Zhaohui, Ng Chee H, Xiang Yu-Tao
Unit of Psychiatry, Department of Public Health and Medicinal Administration, & Institute of Translational Medicine, Faculty of Health Sciences, University of Macau, Macao SAR, China.
Centre for Cognitive and Brain Sciences, University of Macau, Macao SAR, China.
Int J Biol Sci. 2021 Apr 10;17(6):1469-1475. doi: 10.7150/ijbs.58835. eCollection 2021.
Vaccination is an important preventative measure against the coronavirus disease 19 (COVID-19) pandemic. To implement vaccination and immunization programs effectively, it is essential to investigate public attitudes toward COVID-19 vaccines. This study examined the attitudes of Chinese college students toward COVID-19 vaccines and their associated factors. A cross-sectional study was conducted in college students nationwide from December 27, 2020 to January 18, 2021. Attitudes toward COVID-19 vaccines and acceptance of future vaccination programs were assessed. Totally, 2,881 college students participated in this survey; of them, 76.3% (95% CI: 74.8% - 77.9%) were willing to accept a COVID-19 vaccine in the future. Multiple logistic analysis revealed that students living in urban (OR=1.409, 95% CI: 1.152 - 1.724, p=0.001) and those studying health-related courses (OR=1.581, 95% CI: 1.291 - 1.935, p<0.001) were more likely to have a positive attitude toward COVID-19 vaccines. In addition, those who were worried about being infected with COVID-19 (very much vs no, OR=1.690, 95% CI: 1.212-2.356, p=0.002), heard previously about COVID-19 vaccines (OR=1.659, 95% CI: 1.268-2.170, p<0.001), believed that vaccines are safe (Yes vs No, OR=3.570, 95% CI: 1.825-6.980), thought that vaccines can protect people from being infected with COVID-19 (Yes vs No, OR=1.957, 95% CI: 1.286-2.979, p=0.002), and had encouraged their family and friends to have a vaccine (Yes vs No, OR=17.745, 95% CI: 12.271-25.660, p<0.001) had higher acceptance of COVID-19 vaccination. A high rate of acceptance of COVID-19 vaccines was found among Chinese college students. However, vaccine uptake may be reduced by concerns about vaccine safety and efficacy. Alleviating these concerns and enhancing public confidence in vaccines are crucial for future immunization programs against the COVID-19 pandemic.
接种疫苗是预防新型冠状病毒肺炎(COVID-19)大流行的一项重要措施。为有效实施疫苗接种和免疫规划,调查公众对COVID-19疫苗的态度至关重要。本研究调查了中国大学生对COVID-19疫苗的态度及其相关因素。于2020年12月27日至2021年1月18日在全国大学生中开展了一项横断面研究。评估了对COVID-19疫苗的态度以及对未来疫苗接种规划的接受情况。共有2881名大学生参与了此次调查;其中,76.3%(95%CI:74.8%-77.9%)的学生愿意在未来接种COVID-19疫苗。多因素logistic分析显示,居住在城市的学生(OR=1.409,95%CI:1.152-1.724,p=0.001)以及学习与健康相关课程的学生(OR=1.581,95%CI:1.291-1.935,p<0.001)对COVID-19疫苗的态度更积极。此外,那些担心感染COVID-19的学生(非常担心vs不担心,OR=1.690,95%CI:1.212-2.356,p=0.002)、之前听说过COVID-19疫苗的学生(OR=1.659,95%CI:1.268-2.170,p<0.001)、认为疫苗安全的学生(是vs否,OR=3.570,95%CI:1.825-6.980)、认为疫苗可预防COVID-19感染的学生(是vs否,OR=1.957,95%CI:1.286-2.979,p=0.002)以及曾鼓励家人和朋友接种疫苗的学生(是vs否,OR=17.745,95%CI:12.271-25.660,p<0.001)对COVID-19疫苗接种的接受度更高。中国大学生对COVID-19疫苗的接受率较高。然而,对疫苗安全性和有效性的担忧可能会降低疫苗接种率。缓解这些担忧并增强公众对疫苗的信心对于未来针对COVID-19大流行的免疫规划至关重要。