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长期牙周维护期间牙齿丧失的预测因素:更新的系统评价。

Predictors of tooth loss during long-term periodontal maintenance: An updated systematic review.

机构信息

Clinical Research Unit (CRU), Centro de Investigação Interdisciplinar Egas Moniz (CiiEM), Egas Moniz-Cooperativa de Ensino Superior, Caparica, Almada, Portugal.

Periodontology Department, Egas Moniz Dental Clinic (EMDC), Egas Moniz-Cooperativa de Ensino Superior, Caparica, Almada, Portugal.

出版信息

J Clin Periodontol. 2021 Aug;48(8):1019-1036. doi: 10.1111/jcpe.13488. Epub 2021 May 29.

Abstract

AIM

To evaluate the risk factors / predictors of tooth loss in patients with periodontitis who underwent periodontal therapy and long-term periodontal maintenance (PM).

MATERIAL AND METHODS

PubMed, CENTRAL, EMBASE, Web of Science, LILACS and Scholar were searched up to and including September 2020. Studies limited to periodontitis patients who underwent active periodontal therapy (APT) and followed a regular PM programme with 5 years follow-up minimum were eligible for inclusion in this review. Studies were included if they reported data on tooth loss during PM. Random effects meta-analyses of number of tooth loss per patient per year were conducted.

RESULTS

Thirty-six papers regarding thirty-three studies were included in this review, with three prospective 30 retrospective trials. Subgroup meta-analysis showed no differences between prospective and retrospective studies, with an average of 0.1 tooth loss per year per patient (p < 0.001). Maxillary and molar teeth were more susceptible to be extracted during long-term PM. Baseline characteristics (smoking, diabetes mellitus, cardiovascular disease, being male and teeth with furcation lesions) showed no significance as predictor of tooth loss through meta-regression. The percentage of tooth loss due to periodontal reasons ranged from 0.45% to 14.4%. The individual outcomes in each study evidenced different patient-related factors (age and smoking) and tooth-related factors (i.e. tooth type and location) were associated with tooth loss during PM.

CONCLUSION

The majority of patients undergoing long-term PM have not lost teeth. On average, long-term PM effectively causes the loss of 1 tooth per patient every 10 years. Additional prospective trials may confirm these results.

摘要

目的

评估牙周炎患者在接受牙周治疗和长期牙周维护(PM)后牙齿缺失的风险因素/预测因素。

材料和方法

检索了 PubMed、CENTRAL、EMBASE、Web of Science、LILACS 和 Scholar,检索时间截至 2020 年 9 月。本综述纳入的研究对象为接受积极牙周治疗(APT)并遵循至少 5 年定期 PM 计划的牙周炎患者。如果研究报告了 PM 期间牙齿缺失的数据,则纳入研究。对每年每位患者缺失的牙齿数量进行随机效应荟萃分析。

结果

本综述共纳入 36 篇文章,涉及 33 项研究,其中前瞻性研究 3 项,回顾性研究 30 项。亚组荟萃分析显示,前瞻性和回顾性研究之间无差异,平均每年每位患者缺失 0.1 颗牙齿(p<0.001)。上颌和磨牙在长期 PM 中更容易被拔除。基线特征(吸烟、糖尿病、心血管疾病、男性和有分叉病变的牙齿)通过元回归分析显示与牙齿缺失无关。因牙周原因导致的牙齿缺失百分比范围为 0.45%至 14.4%。每个研究的个体结果均表明不同的患者相关因素(年龄和吸烟)和牙齿相关因素(即牙齿类型和位置)与 PM 期间的牙齿缺失有关。

结论

大多数接受长期 PM 的患者并未失去牙齿。平均而言,长期 PM 每 10 年有效导致每位患者缺失 1 颗牙齿。可能需要进一步的前瞻性试验来证实这些结果。

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