非 ABO 血型红细胞抗体与 COVID-19 风险。

Non-ABO red cell antibodies and risk of COVID-19.

机构信息

Department of Medicine, St. Michael's Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario, M5B 1W8 Canada; ICES, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5 Canada.

Department of Medicine, St. Michael's Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario, M5B 1W8 Canada.

出版信息

Int J Infect Dis. 2021 Jul;108:179-182. doi: 10.1016/j.ijid.2021.05.038. Epub 2021 May 19.

DOI:10.1016/j.ijid.2021.05.038

PMID:34022334

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8132504/

Abstract

It is not known whether non-ABO antibodies confer any protective effect against SARS-CoV-2 infection or COVID-19 severe illness alone or in conjunction with O blood group. This cohort study included 413 576 persons in Ontario, Canada with known ABO blood group and non-ABO antibody screen status, who subsequently underwent SARS-CoV-2 viral RNA polymerase chain reaction testing between January and November 2020. The risk of SARS-CoV-2 infection or COVID-19 severe illness was not associated with the presence of non-ABO antibodies, even among persons with O blood group.

摘要

目前尚不清楚非 ABO 抗体是否对单独或与 O 型血一起预防 SARS-CoV-2 感染或 COVID-19 重症有任何保护作用。本队列研究纳入了加拿大安大略省的 413576 名已知 ABO 血型和非 ABO 抗体筛查状态的人群，他们随后于 2020 年 1 月至 11 月期间接受了 SARS-CoV-2 病毒 RNA 聚合酶链反应检测。非 ABO 抗体的存在与 SARS-CoV-2 感染或 COVID-19 重症的风险无关，即使是在 O 型血人群中也是如此。