Division of Hematology Oncology, Department of Medicine, O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL.
Department of Obstetrics and Gynecology and the Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL.
Am Soc Clin Oncol Educ Book. 2021 Jun;41:e29-e46. doi: 10.1200/EDBK_319929.
Persistent disparities in the burden of breast cancer between African Americans and White Americans have been documented over many decades. Features characterizing breast cancer in the African American community include a 40% higher mortality rate, younger age distribution, greater advanced-stage distribution, increased risk of biologically aggressive disease such as the triple-negative phenotype, and increased incidence of male breast cancer. Public health experts, genetics researchers, clinical trialists, multidisciplinary oncology teams, and advocates must collaborate to comprehensively address the multifactorial etiology of and remedies for breast cancer disparities. Efforts to achieve breast health equity through improved access to affordable, high-quality care are especially imperative in the context of the COVID-19 pandemic and its disproportionately high economic toll on African Americans.
几十年来,非裔美国人和白种人之间乳腺癌负担的持续差异一直有记录。非裔美国人社区乳腺癌的特征包括死亡率高出 40%、发病年龄更小、更晚期的分布、生物侵袭性疾病(如三阴性表型)的风险增加,以及男性乳腺癌的发病率增加。公共卫生专家、遗传研究人员、临床试验人员、多学科肿瘤团队和倡导者必须合作,全面解决乳腺癌差异的多因素病因和治疗方法。在 COVID-19 大流行及其对非裔美国人造成的不成比例的高经济损失的背景下,通过改善获得负担得起的高质量护理的机会来实现乳房健康公平的努力尤为重要。