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[西班牙中部和东部地区新冠疫情对急性细支气管炎住院治疗的影响]

[Consequences of COVID-19 pandemic over acute bronchiolitis hospitalizations in the center and east of Spain].

作者信息

Rius-Peris Juan Manuel, Lucas-García Jesús, García-Peris Mónica, Escrivá Tomás Pascual, Sequí-Canet José Miguel, González de Dios Javier

机构信息

Hospital Universitario Virgen de la Luz, Cuenca, España.

Hospital General Universitario de Castellón, Castellón, España.

出版信息

An Pediatr (Barc). 2021 Nov;95(5):345-353. doi: 10.1016/j.anpedi.2021.06.008. Epub 2021 Jun 23.

Abstract

INTRODUCTION

Non-pharmaceutical interventions that have been implemented in southern hemisphere countries because of COVID-19 pandemic declaration in March 2020, have evidenced some unexpected changes in the way of spreading of many other viruses. This study as a part of ECEALHBA's Project, reports the consequences of COVID-19 pandemic over 2020-2021 bronchiolitis epidemic period in the Central and Eastern regions of Spain.

METHOD

Multicenter, observational, descriptive and ambispective study of admitted infants with the diagnosis of bronchiolitis in 16 Spanish hospitals involved in the investigation project. Five epidemic periods previous to COVID-19 pandemic, from 2015 to 2020, were compared with the current one, 2020-2021, in both a qualitative and quantitative manner.

RESULTS

Total of 4643 infants were admitted to the participating hospitals along the study period. Pandemic season hospital admissions for bronchiolitis were 94.1% lower than in pre-pandemic period. December and January were peak months for bronchiolitis admissions during pre-pandemic period, but September was the peak month during pandemic year. There was a progressive decrease of admissions from this moment until the end of the follow up, in April 2021. Rhinovirus has been the commonest etiology for bronchiolitis in 2020-2021 epidemic period of bronchiolitis.

CONCLUSIONS

Some of the non-pharmaceutical interventions initiated because of COVID-19 pandemic are probably related to the dramatic decrease of bronchiolitis cases in 2020-2021 season. It would be rewarding to purpose novel research to clarify how these simple interventions can be useful, close to vaccines and antiviral drugs, to achieve the goal of avoiding the spread of respiratory viruses in pediatric population.

摘要

引言

由于2020年3月宣布的新冠疫情,南半球国家实施了非药物干预措施,这证明了许多其他病毒传播方式发生了一些意想不到的变化。本研究作为欧洲儿童环境与健康行为协会项目的一部分,报告了新冠疫情对西班牙中部和东部地区2020 - 2021年细支气管炎流行期的影响。

方法

对参与调查项目的16家西班牙医院中诊断为细支气管炎的入院婴儿进行多中心、观察性、描述性和前瞻性研究。将新冠疫情之前的五个流行期(2015年至2020年)与当前的2020 - 2021年流行期进行了定性和定量比较。

结果

在研究期间,共有4643名婴儿入住参与研究的医院。疫情期间细支气管炎的住院人数比疫情前降低了94.1%。疫情前,12月和1月是细支气管炎住院人数的高峰月,但2020年疫情期间9月是高峰月。从此时到2021年4月随访结束,住院人数逐渐减少。在2020 - 2021年细支气管炎流行期,鼻病毒一直是细支气管炎最常见的病因。

结论

因新冠疫情启动的一些非药物干预措施可能与2020 - 2021年季节细支气管炎病例的急剧减少有关。开展新的研究以阐明这些简单干预措施如何能像疫苗和抗病毒药物一样有效,从而实现避免呼吸道病毒在儿童群体中传播的目标,将是很有意义的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6284/8220935/63b8eaaf32b9/gr1_lrg.jpg

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