Zhonghua Nei Ke Za Zhi. 2021 Jul 1;60(7):599-614. doi: 10.3760/cma.j.cn112137-20210425-00991.
Hepatocellular carcinoma (HCC) is a malignancy originating from liver cells. Hepatitis B virus (HBV) is the major etiological factor contributed to the development of HCC in China. Pathologically, HCC is usually characterized of hypervascularity. The rationale of transarterial chemoembolization (TACE) is that the intraarterial infusion of cytotoxic agents followed by embolization of the tumor-feeding blood vessels causes a strong tumor killing effect. TACE is the most widely used primary treatment for unresectable HCC. In 2018, Chinese clinical practice guidelines for transarterial chemoembolization of hepatocellular carcinoma were published by Chinese College of Interventionalists. After several clinical and scientific advances are achieved, a new version of practice guidelines is updated in 2021.
肝细胞癌(HCC)是一种起源于肝细胞的恶性肿瘤。乙型肝炎病毒(HBV)是中国肝细胞癌发生发展的主要病因。在病理上,肝细胞癌通常以血管丰富为特征。经动脉化疗栓塞术(TACE)的原理是动脉内注入细胞毒性药物,随后栓塞肿瘤供血血管,从而产生强大的肿瘤杀伤作用。TACE是不可切除肝细胞癌最广泛应用的主要治疗方法。2018年,中国介入医师学会发布了《肝细胞癌经动脉化疗栓塞临床实践指南》。在取得多项临床和科学进展后,2021年更新了新版实践指南。