Department of Chemistry & Physics, Augusta University, Augusta, GA 30912, USA.
Molecules. 2021 Oct 14;26(20):6197. doi: 10.3390/molecules26206197.
Viral infections are among the most complex medical problems and have been a major threat to the economy and global health. Several epidemics and pandemics have occurred due to viruses, which has led to a significant increase in mortality and morbidity rates. Natural products have always been an inspiration and source for new drug development because of their various uses. Among all-natural sources, plant sources are the most dominant for the discovery of new therapeutic agents due to their chemical and structural diversity. Despite the traditional use and potential source for drug development, natural products have gained little attention from large pharmaceutical industries. Several plant extracts and isolated compounds have been extensively studied and explored for antiviral properties against different strains of viruses. In this review, we have compiled antiviral plant extracts and natural products isolated from plants reported since 2015.
病毒感染是最复杂的医学问题之一,一直是经济和全球健康的主要威胁。由于病毒的原因,已经发生了几次传染病和大流行,导致死亡率和发病率显著上升。天然产物一直是新药开发的灵感和来源,因为它们有多种用途。在所有天然来源中,由于其化学和结构多样性,植物来源是发现新治疗剂的最主要来源。尽管有传统的用途和药物开发的潜在来源,但天然产物很少受到大型制药行业的关注。已经对几种植物提取物和分离化合物进行了广泛的研究和探索,以寻找针对不同病毒株的抗病毒特性。在这篇综述中,我们汇编了自 2015 年以来报道的具有抗病毒活性的植物提取物和从植物中分离得到的天然产物。