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人类微生物组研究报告指南:STORMS 清单。

Reporting guidelines for human microbiome research: the STORMS checklist.

机构信息

CUNY Graduate School of Public Health and Health Policy, Institute for Implementation Science in Public Health, New York, NY, USA.

University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

出版信息

Nat Med. 2021 Nov;27(11):1885-1892. doi: 10.1038/s41591-021-01552-x. Epub 2021 Nov 17.

Abstract

The particularly interdisciplinary nature of human microbiome research makes the organization and reporting of results spanning epidemiology, biology, bioinformatics, translational medicine and statistics a challenge. Commonly used reporting guidelines for observational or genetic epidemiology studies lack key features specific to microbiome studies. Therefore, a multidisciplinary group of microbiome epidemiology researchers adapted guidelines for observational and genetic studies to culture-independent human microbiome studies, and also developed new reporting elements for laboratory, bioinformatics and statistical analyses tailored to microbiome studies. The resulting tool, called 'Strengthening The Organization and Reporting of Microbiome Studies' (STORMS), is composed of a 17-item checklist organized into six sections that correspond to the typical sections of a scientific publication, presented as an editable table for inclusion in supplementary materials. The STORMS checklist provides guidance for concise and complete reporting of microbiome studies that will facilitate manuscript preparation, peer review, and reader comprehension of publications and comparative analysis of published results.

摘要

人类微生物组研究具有特别的跨学科性质,因此组织和报告涵盖流行病学、生物学、生物信息学、转化医学和统计学的研究结果是一项挑战。常用的观察性或遗传流行病学研究报告指南缺乏针对微生物组研究的特定关键特征。因此,一组多学科的微生物组流行病学研究人员对观察性和遗传研究的指南进行了改编,使其适用于非培养依赖性的人类微生物组研究,并针对实验室、生物信息学和统计分析开发了新的报告要素,以适应微生物组研究。由此产生的工具称为“加强微生物组研究的组织和报告”(STORMS),由一个 17 项清单组成,分为六个部分,与科学出版物的典型部分相对应,以可编辑表格的形式呈现,可作为补充材料的一部分。STORMS 清单为简明完整地报告微生物组研究提供了指导,有助于准备稿件、同行评审以及读者理解出版物和比较分析已发表结果。

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