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诊断管理:合理的检查和明智的治疗。

Diagnostic Stewardship: Appropriate Testing and Judicious Treatments.

机构信息

Division of Infectious Diseases, Children's Hospital of Philadelphia, 3401 Civic Center Boulevard, Philadelphia, PA 19104, USA.

Department of Critical Care, Gundersen Lutheran Medical Center, 1900 South Avenue, Mail Stop LM3-001, La Crosse, WI 54601, USA; Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

出版信息

Crit Care Clin. 2022 Jan;38(1):69-87. doi: 10.1016/j.ccc.2021.09.002.

Abstract

Diagnostic stewardship encompasses the entire diagnosis-to-treatment paradigm in the intensive care unit (ICU). Initially born of the antimicrobial stewardship movement, contemporary diagnostic stewardship aims to promote timely and appropriate diagnostic testing that directly links to management decisions. In the stewardship framework, excessive diagnostic testing in low probability cases is discouraged due to its tendency to generate false-positive results, which have their own downstream consequences. Though the evidence basis for diagnostic stewardship initiatives in the ICU is nascent and largely limited to retrospective analyses, available literature generally suggests that these initiatives are safe, feasible, and associated with similar patient outcomes. As diagnostic testing of critically ill patients becomes increasingly sophisticated in the ensuing decade, a stewardship mindset will aid bedside clinicians in interpreting and incorporating new diagnostic strategies in the ICU.

摘要

诊断管理涵盖了重症监护病房(ICU)中从诊断到治疗的整个过程。它最初源于抗菌药物管理运动,目前的诊断管理旨在促进及时和适当的诊断测试,这些测试直接与管理决策相关联。在管理框架中,由于低概率情况下的过度诊断测试容易产生假阳性结果,因此不鼓励这种做法,因为这会带来其自身的下游后果。尽管 ICU 中诊断管理计划的证据基础尚处于初期阶段,并且主要限于回顾性分析,但现有文献普遍表明,这些计划是安全、可行的,并且与类似的患者结局相关。随着未来十年对危重症患者的诊断测试变得越来越复杂,管理思维将帮助床边临床医生在 ICU 中解释和采用新的诊断策略。

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