Department of Human Evolutionary Biology, Harvard University, Cambridge, MA, USA.
Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Nature. 2022 Jan;601(7894):588-594. doi: 10.1038/s41586-021-04287-4. Epub 2021 Dec 22.
Present-day people from England and Wales have more ancestry derived from early European farmers (EEF) than did people of the Early Bronze Age. To understand this, here we generated genome-wide data from 793 individuals, increasing data from the Middle to the Late Bronze Age and Iron Age in Britain by 12-fold, and western and central Europe by 3.5-fold. Between 1000 and 875 BC, EEF ancestry increased in southern Britain (England and Wales) but not northern Britain (Scotland) due to incorporation of migrants who arrived at this time and over previous centuries, and who were genetically most similar to ancient individuals from France. These migrants contributed about half the ancestry of people of England and Wales from the Iron Age, thereby creating a plausible vector for the spread of early Celtic languages into Britain. These patterns are part of a broader trend of EEF ancestry becoming more similar across central and western Europe in the Middle to the Late Bronze Age, coincident with archaeological evidence of intensified cultural exchange. There was comparatively less gene flow from continental Europe during the Iron Age, and the independent genetic trajectory in Britain is also reflected in the rise of the allele conferring lactase persistence to approximately 50% by this time compared to approximately 7% in central Europe where it rose rapidly in frequency only a millennium later. This suggests that dairy products were used in qualitatively different ways in Britain and in central Europe over this period.
当今的英格兰和威尔士人比青铜时代早期的人拥有更多源自早期欧洲农民(EEF)的祖先。为了理解这一点,我们从 793 个人体中生成了全基因组数据,使英国从中石器时代到青铜时代晚期和铁器时代的数据增加了 12 倍,使欧洲西部和中部的数据增加了 3.5 倍。在公元前 1000 年至 875 年期间,由于此时和前几个世纪到达的移民的融合,英国南部(英格兰和威尔士)的 EEF 祖先增加,但英国北部(苏格兰)没有增加,这些移民在基因上与来自法国的古代个体最为相似。这些移民对英格兰和威尔士铁器时代的人的祖先贡献了约一半,从而为早期凯尔特语言在英国的传播创造了一个合理的载体。这些模式是 EEF 祖先在中石器时代到青铜时代晚期在欧洲中部和西部变得更加相似的更广泛趋势的一部分,与考古证据表明文化交流的加强相一致。在铁器时代,来自欧洲大陆的基因流动相对较少,英国的独立遗传轨迹也反映在此时乳糖酶持久等位基因的上升,此时英国的上升到大约 50%,而在中欧,该等位基因仅在一千年后才迅速上升到大约 7%。这表明在这段时间里,奶制品在英国和中欧的使用方式存在质的不同。