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疼痛、疲劳和情绪健康应如何纳入炎症性肠病最佳管理的治疗目标?

How Should Pain, Fatigue, and Emotional Wellness Be Incorporated Into Treatment Goals for Optimal Management of Inflammatory Bowel Disease?

机构信息

Department of Medicine-Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, New York.

Department of Psychiatry and Behavioral Neuroscience, The University of Chicago, Chicago, Illinois.

出版信息

Gastroenterology. 2022 Apr;162(5):1439-1451. doi: 10.1053/j.gastro.2021.08.060. Epub 2022 Jan 4.

Abstract

Early diagnosis and the optimal control of inflammation, with a continuous cycle of assessment, treatment, monitoring, and adjustment of therapy, is best practice for the management of inflammatory bowel disease. However, patients express frustration with ongoing challenging symptoms, often discordant with inflammation, including abdominal pain, fatigue, depression, anxiety, and emotional wellness; these are often not optimally addressed by inflammatory bowel disease clinicians due to lack of time or resources. This review will highlight the burden of these symptoms and issues, suggest ways of assessing these in clinical practice, highlight the importance of acknowledging and validating the symptoms and issues with patients, reassuring them that they are being heard, and discuss different possible models of service delivery for psychosocial support, from fully integrated gastropsychology models to referral pathways that optimize community support. We suggest the importance of the treat-to-target concept, where the target is not only control of inflammation but also emotional wellness.

摘要

早期诊断和炎症的最佳控制,以及持续的评估、治疗、监测和治疗调整循环,是炎症性肠病管理的最佳实践。然而,患者对持续存在的具有挑战性的症状感到沮丧,这些症状常常与炎症不一致,包括腹痛、疲劳、抑郁、焦虑和情绪健康;由于缺乏时间或资源,炎症性肠病临床医生往往无法很好地解决这些问题。这篇综述将强调这些症状和问题的负担,提出在临床实践中评估这些症状的方法,强调承认和验证患者症状和问题的重要性,让他们感到自己的声音被听到,并讨论不同的心理社会支持服务提供模式,从完全整合的胃肠心理学模式到优化社区支持的转诊途径。我们建议重视治疗目标的概念,其目标不仅是控制炎症,还有情绪健康。

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