School of Aging Studies, University of South Florida, 4202 E. Fowler Avenue, MHC 1344, Tampa, FL, 33620, USA.
Department of Psychiatry, Statistics and Biostatistics, University of Pittsburgh, Pittsburgh, PA, USA.
Sci Rep. 2022 Feb 7;12(1):2023. doi: 10.1038/s41598-022-05203-0.
We examined whether subjectively and objectively measured sleep health composites have a relationship with heart disease. 6,820 adults (M = 53.4 years) from the Midlife in the United States study provided self-reported sleep characteristics and heart disease history. A smaller sample (n = 663) provided actigraphy sleep data. We tested two sleep health composites, based on self-report only and both self-report and actigraphy, across multiple sleep dimensions. We used a weighted sum approach, where higher scores indicated more sleep health problems. Modified Poisson regressions adjusted for sociodemographics and known risk factors. Having more sleep health problems was associated with a higher risk of heart disease using the self-report sleep health composite (aRR = 54%, P < .001) and the actigraphy/self-report composite (aRR = 141%, P < .001). Individual sleep dimensions of satisfaction, alertness, and efficiency (from the self-report composite) and regularity, satisfaction, and timing (from the actigraphy/self-report composite) were associated with the risk of heart disease. The effect size of each sleep health composite was larger than the individual sleep dimensions. Race moderated the association between the actigraphy/self-report sleep health composite and heart disease. There was no significant moderation by sex. Findings suggest poorer sleep health across multiple dimensions may contribute to heart disease risk among middle-aged adults.
我们研究了主观和客观测量的睡眠健康综合指标与心脏病之间是否存在关系。来自美国中年生活研究的 6820 名成年人(平均年龄 53.4 岁)提供了自我报告的睡眠特征和心脏病史。一小部分(n=663)提供了活动记录仪睡眠数据。我们测试了两种睡眠健康综合指标,一种仅基于自我报告,另一种同时基于自我报告和活动记录仪,涵盖了多个睡眠维度。我们使用加权总和方法,得分越高表示睡眠健康问题越多。修正泊松回归调整了社会人口统计学和已知的风险因素。使用自我报告的睡眠健康综合指标(ARR=54%,P<.001)和活动记录仪/自我报告综合指标(ARR=141%,P<.001),睡眠健康问题越多,患心脏病的风险越高。个体睡眠维度的满意度、警觉度和效率(来自自我报告综合指标)以及规律性、满意度和时间安排(来自活动记录仪/自我报告综合指标)与心脏病风险相关。每个睡眠健康综合指标的效应大小都大于单个睡眠维度。种族调节了活动记录仪/自我报告睡眠健康综合指标与心脏病之间的关联。性别没有显著调节作用。研究结果表明,多个维度的睡眠健康状况较差可能会增加中年成年人患心脏病的风险。