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通过额外食用预洗“富士”苹果皮的抗肥胖和抗氧化活性作用

Effect of Anti-Obesity and Antioxidant Activity through the Additional Consumption of Peel from 'Fuji' Pre-Washed Apple.

作者信息

Ko Da-Yeong, Ku Kang-Mo

机构信息

Department of Horticulture, College of Agriculture and Life Sciences, Chonnam National University, Gwangju 61186, Korea.

Interdisciplinary Program in IT-Bio Convergence System, Chonnam National University, Gwangju 61186, Korea.

出版信息

Foods. 2022 Feb 9;11(4):497. doi: 10.3390/foods11040497.

Abstract

There is limited information on the health effects of apple peel taken from 'Fuji' ( Mill) apples washed with ozonated water. To clarify the health-promoting effects of peel, the triterpenoids (ursolic acid and oleanolic acid) were quantified with gas chromatograph-mass spectrometry. Anti-obesity effects of apple peel extract on the 3T3-L1 pre-adipocyte cell were compared with apple flesh, whole apple, and ursolic acid. The peel extract treatment with 3.30 ± 1.05 μM of ursolic acid significantly suppressed ( < 0.05) the lipid accumulation compared with the content in flesh, and a similar level was reached in the 5 μM ursolic acid positive control group. In the peel extract and ursolic acid treatment groups, the C16:0 concentration was significantly inhibited ( < 0.05), implying the anti-obesity effect of ursolic acid on the 3T3-L1 cell. Moreover, apple peel contributed 41% of the total flavonoids content and 31% of the phenolic contents of the whole apple, but only accounted for less than 10% of the whole apple (weight basis). This study's results offer basic data on pre-washed apple as a health functional food, offering information about the health benefits of apple peel, calculated based on the partial ratio in the whole apple.

摘要

关于用臭氧水清洗过的“富士”(Mill)苹果的果皮对健康影响的信息有限。为了阐明果皮的健康促进作用,采用气相色谱 - 质谱法对三萜类化合物(熊果酸和齐墩果酸)进行了定量分析。将苹果皮提取物对3T3 - L1前脂肪细胞的抗肥胖作用与苹果果肉、整个苹果以及熊果酸进行了比较。与果肉中的含量相比,用3.30±1.05μM熊果酸处理的果皮提取物显著抑制(<0.05)了脂质积累,并且在5μM熊果酸阳性对照组中达到了类似水平。在果皮提取物和熊果酸处理组中,C16:0浓度显著受到抑制(<0.05),这意味着熊果酸对3T3 - L1细胞具有抗肥胖作用。此外,苹果皮占整个苹果总黄酮含量的41%和酚类物质含量的31%,但仅占整个苹果重量的不到10%。本研究结果为预洗苹果作为健康功能食品提供了基础数据,基于其在整个苹果中的占比,提供了有关苹果皮健康益处的信息。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8ce/8871014/2b6bcf097a26/foods-11-00497-g001.jpg

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